Breaking boundaries of hybrid photodetector: A novel approach for high-speed TCSPC with minimal distortion
Time-Correlated Single-Photon Counting (TCSPC) enables the measurement of low-intensity optical signals with sub-picosecond timing resolution. Its performance has long been limited by pile-up distortion, which restricts acquisition rates to a small fraction (typically 5%) of the laser excitation rat...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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AIP Publishing LLC
2025-06-01
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| Series: | APL Photonics |
| Online Access: | http://dx.doi.org/10.1063/5.0268205 |
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| author | P. Daniele G. Fratta I. Labanca G. Acconcia I. Rech |
| author_facet | P. Daniele G. Fratta I. Labanca G. Acconcia I. Rech |
| author_sort | P. Daniele |
| collection | DOAJ |
| description | Time-Correlated Single-Photon Counting (TCSPC) enables the measurement of low-intensity optical signals with sub-picosecond timing resolution. Its performance has long been limited by pile-up distortion, which restricts acquisition rates to a small fraction (typically 5%) of the laser excitation rate. In this work, we break through these limitations in fluorescence measurements by harnessing the power of a hybrid photodetector and validating a novel, constraint-free methodology that removes pile-up distortion, enabling high precision in lifetime estimation. The mathematical framework underlying this method not only makes it possible to overcome the traditional distortion but also addresses previously unexplored error sources. For the first time, we present a real-time processing algorithm that compensates for hardware-induced distortions, achieving a comprehensive fluorescence histogram correction. Remarkably, with our approach, we achieve a count rate as high as 121% of the excitation rate, setting a new benchmark in TCSPC performance and representing a transformative leap forward in the capability of the technology to deliver high-speed and high-precision measurements. |
| format | Article |
| id | doaj-art-7ab0e4d922f049bbadd88fb8b1f3b541 |
| institution | OA Journals |
| issn | 2378-0967 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | AIP Publishing LLC |
| record_format | Article |
| series | APL Photonics |
| spelling | doaj-art-7ab0e4d922f049bbadd88fb8b1f3b5412025-08-20T02:38:29ZengAIP Publishing LLCAPL Photonics2378-09672025-06-01106060803060803-1010.1063/5.0268205Breaking boundaries of hybrid photodetector: A novel approach for high-speed TCSPC with minimal distortionP. Daniele0G. Fratta1I. Labanca2G. Acconcia3I. Rech4Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, via Golgi 40, 20133 Milan, ItalyDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, via Golgi 40, 20133 Milan, ItalyDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, via Golgi 40, 20133 Milan, ItalyDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, via Golgi 40, 20133 Milan, ItalyDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, via Golgi 40, 20133 Milan, ItalyTime-Correlated Single-Photon Counting (TCSPC) enables the measurement of low-intensity optical signals with sub-picosecond timing resolution. Its performance has long been limited by pile-up distortion, which restricts acquisition rates to a small fraction (typically 5%) of the laser excitation rate. In this work, we break through these limitations in fluorescence measurements by harnessing the power of a hybrid photodetector and validating a novel, constraint-free methodology that removes pile-up distortion, enabling high precision in lifetime estimation. The mathematical framework underlying this method not only makes it possible to overcome the traditional distortion but also addresses previously unexplored error sources. For the first time, we present a real-time processing algorithm that compensates for hardware-induced distortions, achieving a comprehensive fluorescence histogram correction. Remarkably, with our approach, we achieve a count rate as high as 121% of the excitation rate, setting a new benchmark in TCSPC performance and representing a transformative leap forward in the capability of the technology to deliver high-speed and high-precision measurements.http://dx.doi.org/10.1063/5.0268205 |
| spellingShingle | P. Daniele G. Fratta I. Labanca G. Acconcia I. Rech Breaking boundaries of hybrid photodetector: A novel approach for high-speed TCSPC with minimal distortion APL Photonics |
| title | Breaking boundaries of hybrid photodetector: A novel approach for high-speed TCSPC with minimal distortion |
| title_full | Breaking boundaries of hybrid photodetector: A novel approach for high-speed TCSPC with minimal distortion |
| title_fullStr | Breaking boundaries of hybrid photodetector: A novel approach for high-speed TCSPC with minimal distortion |
| title_full_unstemmed | Breaking boundaries of hybrid photodetector: A novel approach for high-speed TCSPC with minimal distortion |
| title_short | Breaking boundaries of hybrid photodetector: A novel approach for high-speed TCSPC with minimal distortion |
| title_sort | breaking boundaries of hybrid photodetector a novel approach for high speed tcspc with minimal distortion |
| url | http://dx.doi.org/10.1063/5.0268205 |
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