Representativeness in population-based studies of older adults: five waves of cross-sectional examinations in the Gothenburg H70 Birth Cohort Study
Objectives To describe representativeness in the Gothenburg H70 1930 Birth Cohort Study.Design Repeated cross-sectional examinations of a population-based study.Setting Gothenburg, Sweden.Participants All residents of Gothenburg, Sweden, born on specific birth dates in 1930 were invited to a compreh...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2022-12-01
|
| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/12/e068165.full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850187887641886720 |
|---|---|
| author | Margda Waern Ingmar Skoog Lena Johansson Xinxin Guo Silke Kern Erik Joas Hanna Wetterberg Lina Rydén Felicia Ahlner Hanna Falk Erhag Pia Gudmundsson Madeleine Mellqvist Fässberg Jenna Najar Mats Ribbe Therese Rydberg Sterner Jessica Samuelsson Simona Sacuiu Robert Sigström Johan Skoog Anna Zettergren |
| author_facet | Margda Waern Ingmar Skoog Lena Johansson Xinxin Guo Silke Kern Erik Joas Hanna Wetterberg Lina Rydén Felicia Ahlner Hanna Falk Erhag Pia Gudmundsson Madeleine Mellqvist Fässberg Jenna Najar Mats Ribbe Therese Rydberg Sterner Jessica Samuelsson Simona Sacuiu Robert Sigström Johan Skoog Anna Zettergren |
| author_sort | Margda Waern |
| collection | DOAJ |
| description | Objectives To describe representativeness in the Gothenburg H70 1930 Birth Cohort Study.Design Repeated cross-sectional examinations of a population-based study.Setting Gothenburg, Sweden.Participants All residents of Gothenburg, Sweden, born on specific birth dates in 1930 were invited to a comprehensive health examination at ages 70, 75, 79, 85 and 88. The number of participants at each examination was 524 at age 70, 767 at age 75, 580 at age 79, 416 at age 85, and 258 at age 88.Primary outcome measures We compared register data on sociodemographic characteristics and hospital discharge diagnoses between participants and (1) refusals, (2) all same-aged individuals in Gothenburg and (3) all same-aged individuals in Sweden. We also compared mortality rates between participants and refusals.Results Refusal rate increased with age. At two or more examination waves, participants compared with refusals had higher educational level, more often had osteoarthritis, had lower mortality rates, had lower prevalence of neuropsychiatric, alcohol-related and cardiovascular disorders, and were more often married. At two examination waves, participants compared with same-aged individuals in Gothenburg had higher education and were more often born in Sweden. At two examination waves or more, participants compared with same-aged individuals in Sweden had higher education, had higher average income, less often had ischaemic heart disease, were less often born in Sweden and were more often divorced.Conclusions Participants were more similar to the target population in Gothenburg than to refusals and same-aged individuals in Sweden. Our study shows the importance of having different comparison groups when assessing representativeness of population studies, which is important in evaluating generalisability of results. The study also contributes unique and up-to-date knowledge about participation bias in these high age groups. |
| format | Article |
| id | doaj-art-7aa59fdf86ed4f86aaecc6a5c616e5d1 |
| institution | OA Journals |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-7aa59fdf86ed4f86aaecc6a5c616e5d12025-08-20T02:16:01ZengBMJ Publishing GroupBMJ Open2044-60552022-12-01121210.1136/bmjopen-2022-068165Representativeness in population-based studies of older adults: five waves of cross-sectional examinations in the Gothenburg H70 Birth Cohort StudyMargda Waern0Ingmar Skoog1Lena Johansson2Xinxin Guo3Silke Kern4Erik Joas5Hanna Wetterberg6Lina Rydén7Felicia Ahlner8Hanna Falk Erhag9Pia Gudmundsson10Madeleine Mellqvist Fässberg11Jenna Najar12Mats Ribbe13Therese Rydberg Sterner14Jessica Samuelsson15Simona Sacuiu16Robert Sigström17Johan Skoog18Anna Zettergren198 Department of Psychotic Disorders, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, SwedenDepartment of Psychiatry and Neurochemistry, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap), Institute of Neuroscience and Physiology, University of Gothenburg, Goteborg, SwedenDepartment of Psychiatry and Neurochemistry, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap), Institute of Neuroscience and Physiology, University of Gothenburg, Goteborg, Sweden1 School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen 518107, Guangdong, ChinaDepartment of Psychiatry and Neurochemistry, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap), Institute of Neuroscience and Physiology, University of Gothenburg, Goteborg, SwedenDepartment of Psychiatry and Neurochemistry, University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, SwedenDepartment of Psychiatry and Neurochemistry, University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, SwedenDepartment of Psychiatry and Neurochemistry, University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, SwedenDepartment of Psychiatry and Neurochemistry, University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, SwedenDepartment of Psychiatry and Neurochemistry, University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, SwedenDepartment of Psychiatry and Neurochemistry, University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, SwedenDepartment of Psychiatry and Neurochemistry, University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, SwedenDepartment of Psychiatry and Neurochemistry, University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, SwedenDepartment of Psychiatry and Neurochemistry, University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, SwedenCentre for Ageing and Health (AGECAP), University of Gothenburg, Gothenburg, SwedenDepartment of Psychiatry and Neurochemistry, University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, SwedenDepartment of Psychiatry and Neurochemistry, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap), Institute of Neuroscience and Physiology, University of Gothenburg, Goteborg, SwedenDepartment of Psychiatry and Neurochemistry, University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, SwedenDepartment of Psychiatry and Neurochemistry, University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, SwedenDepartment of Psychiatry and Neurochemistry, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap), Institute of Neuroscience and Physiology, University of Gothenburg, Goteborg, SwedenObjectives To describe representativeness in the Gothenburg H70 1930 Birth Cohort Study.Design Repeated cross-sectional examinations of a population-based study.Setting Gothenburg, Sweden.Participants All residents of Gothenburg, Sweden, born on specific birth dates in 1930 were invited to a comprehensive health examination at ages 70, 75, 79, 85 and 88. The number of participants at each examination was 524 at age 70, 767 at age 75, 580 at age 79, 416 at age 85, and 258 at age 88.Primary outcome measures We compared register data on sociodemographic characteristics and hospital discharge diagnoses between participants and (1) refusals, (2) all same-aged individuals in Gothenburg and (3) all same-aged individuals in Sweden. We also compared mortality rates between participants and refusals.Results Refusal rate increased with age. At two or more examination waves, participants compared with refusals had higher educational level, more often had osteoarthritis, had lower mortality rates, had lower prevalence of neuropsychiatric, alcohol-related and cardiovascular disorders, and were more often married. At two examination waves, participants compared with same-aged individuals in Gothenburg had higher education and were more often born in Sweden. At two examination waves or more, participants compared with same-aged individuals in Sweden had higher education, had higher average income, less often had ischaemic heart disease, were less often born in Sweden and were more often divorced.Conclusions Participants were more similar to the target population in Gothenburg than to refusals and same-aged individuals in Sweden. Our study shows the importance of having different comparison groups when assessing representativeness of population studies, which is important in evaluating generalisability of results. The study also contributes unique and up-to-date knowledge about participation bias in these high age groups.https://bmjopen.bmj.com/content/12/12/e068165.full |
| spellingShingle | Margda Waern Ingmar Skoog Lena Johansson Xinxin Guo Silke Kern Erik Joas Hanna Wetterberg Lina Rydén Felicia Ahlner Hanna Falk Erhag Pia Gudmundsson Madeleine Mellqvist Fässberg Jenna Najar Mats Ribbe Therese Rydberg Sterner Jessica Samuelsson Simona Sacuiu Robert Sigström Johan Skoog Anna Zettergren Representativeness in population-based studies of older adults: five waves of cross-sectional examinations in the Gothenburg H70 Birth Cohort Study BMJ Open |
| title | Representativeness in population-based studies of older adults: five waves of cross-sectional examinations in the Gothenburg H70 Birth Cohort Study |
| title_full | Representativeness in population-based studies of older adults: five waves of cross-sectional examinations in the Gothenburg H70 Birth Cohort Study |
| title_fullStr | Representativeness in population-based studies of older adults: five waves of cross-sectional examinations in the Gothenburg H70 Birth Cohort Study |
| title_full_unstemmed | Representativeness in population-based studies of older adults: five waves of cross-sectional examinations in the Gothenburg H70 Birth Cohort Study |
| title_short | Representativeness in population-based studies of older adults: five waves of cross-sectional examinations in the Gothenburg H70 Birth Cohort Study |
| title_sort | representativeness in population based studies of older adults five waves of cross sectional examinations in the gothenburg h70 birth cohort study |
| url | https://bmjopen.bmj.com/content/12/12/e068165.full |
| work_keys_str_mv | AT margdawaern representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT ingmarskoog representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT lenajohansson representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT xinxinguo representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT silkekern representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT erikjoas representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT hannawetterberg representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT linaryden representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT feliciaahlner representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT hannafalkerhag representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT piagudmundsson representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT madeleinemellqvistfassberg representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT jennanajar representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT matsribbe representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT thereserydbergsterner representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT jessicasamuelsson representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT simonasacuiu representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT robertsigstrom representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT johanskoog representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy AT annazettergren representativenessinpopulationbasedstudiesofolderadultsfivewavesofcrosssectionalexaminationsinthegothenburgh70birthcohortstudy |