Feasibility and safety of zero-fluoro, “apron-less” approach to repeat pulmonary vein isolation procedures using radiofrequency energy after initial cryoballoon ablation

Abstract We aimed to investigate the feasibility and safety of zero-fluoro approach for the repeat atrial fibrillation (AF) procedures after initial cryoballoon (CB) ablation. We have performed a retrospective study on patients that have undergone repeat pulmonary vein isolation (PVI) procedures in...

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Main Authors: Vedran Velagic, Vedran Pasara, Ivan Prepolec, Andrija Nekic, Zvonimir Katic, Davor Milicic
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-87940-6
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author Vedran Velagic
Vedran Pasara
Ivan Prepolec
Andrija Nekic
Zvonimir Katic
Davor Milicic
author_facet Vedran Velagic
Vedran Pasara
Ivan Prepolec
Andrija Nekic
Zvonimir Katic
Davor Milicic
author_sort Vedran Velagic
collection DOAJ
description Abstract We aimed to investigate the feasibility and safety of zero-fluoro approach for the repeat atrial fibrillation (AF) procedures after initial cryoballoon (CB) ablation. We have performed a retrospective study on patients that have undergone repeat pulmonary vein isolation (PVI) procedures in our institution since zero-fluoro program was initiated in 2020. All patients received CB ablation for the initial procedure. Repeat procedures were performed under conscious sedation and with intracardiac echo (ICE) and 3D mapping system - without the use of fluoroscopy and lead aprons. We have analysed in total 50 patients (76% male, 57.9 ± 10.2 years old), 50% of which suffered from paroxysmal AF. All procedures were successfully performed without the use of fluoroscopy. The mean procedure time was 93.9 ± 27.1 min and the mean RF time was 825 ± 468 s. The mean of 0.98 ± 0.91 veins was reconnected per patient and 36% of patients did not have PV reconnections. In all patients successful PV isolation was performed, confirmed by entry and exit block. No major periprocedural complications were observed. After the mean follow up of 12.5 ± 3.4 months: 68% of mixed AF population patients were free from AF after one year. In our cohort of patients, zero-fluoro, apron-less approach for repeat PVI procedures after index cryoballoon ablation proved to be feasible and safe. Index CB ablation resulted with low rates of PV reconnections and mid-term results after repeat procedures are favourable.
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spelling doaj-art-7a959166ac3342deb50f513609797f602025-02-09T12:33:19ZengNature PortfolioScientific Reports2045-23222025-02-0115111010.1038/s41598-025-87940-6Feasibility and safety of zero-fluoro, “apron-less” approach to repeat pulmonary vein isolation procedures using radiofrequency energy after initial cryoballoon ablationVedran Velagic0Vedran Pasara1Ivan Prepolec2Andrija Nekic3Zvonimir Katic4Davor Milicic5Department of Cardiovascular Diseases, University of Zagreb School of Medicine, University Hospital Centre ZagrebDepartment of Cardiovascular Diseases, University of Zagreb School of Medicine, University Hospital Centre ZagrebDepartment of Cardiovascular Diseases, University of Zagreb School of Medicine, University Hospital Centre ZagrebDepartment of Cardiovascular Diseases, University of Zagreb School of Medicine, University Hospital Centre ZagrebDepartment of Cardiovascular Diseases, University of Zagreb School of Medicine, University Hospital Centre ZagrebDepartment of Cardiovascular Diseases, University of Zagreb School of Medicine, University Hospital Centre ZagrebAbstract We aimed to investigate the feasibility and safety of zero-fluoro approach for the repeat atrial fibrillation (AF) procedures after initial cryoballoon (CB) ablation. We have performed a retrospective study on patients that have undergone repeat pulmonary vein isolation (PVI) procedures in our institution since zero-fluoro program was initiated in 2020. All patients received CB ablation for the initial procedure. Repeat procedures were performed under conscious sedation and with intracardiac echo (ICE) and 3D mapping system - without the use of fluoroscopy and lead aprons. We have analysed in total 50 patients (76% male, 57.9 ± 10.2 years old), 50% of which suffered from paroxysmal AF. All procedures were successfully performed without the use of fluoroscopy. The mean procedure time was 93.9 ± 27.1 min and the mean RF time was 825 ± 468 s. The mean of 0.98 ± 0.91 veins was reconnected per patient and 36% of patients did not have PV reconnections. In all patients successful PV isolation was performed, confirmed by entry and exit block. No major periprocedural complications were observed. After the mean follow up of 12.5 ± 3.4 months: 68% of mixed AF population patients were free from AF after one year. In our cohort of patients, zero-fluoro, apron-less approach for repeat PVI procedures after index cryoballoon ablation proved to be feasible and safe. Index CB ablation resulted with low rates of PV reconnections and mid-term results after repeat procedures are favourable.https://doi.org/10.1038/s41598-025-87940-6Atrial fibrillationCatheter ablationRepeat proceduresZero-fluoroscopy
spellingShingle Vedran Velagic
Vedran Pasara
Ivan Prepolec
Andrija Nekic
Zvonimir Katic
Davor Milicic
Feasibility and safety of zero-fluoro, “apron-less” approach to repeat pulmonary vein isolation procedures using radiofrequency energy after initial cryoballoon ablation
Scientific Reports
Atrial fibrillation
Catheter ablation
Repeat procedures
Zero-fluoroscopy
title Feasibility and safety of zero-fluoro, “apron-less” approach to repeat pulmonary vein isolation procedures using radiofrequency energy after initial cryoballoon ablation
title_full Feasibility and safety of zero-fluoro, “apron-less” approach to repeat pulmonary vein isolation procedures using radiofrequency energy after initial cryoballoon ablation
title_fullStr Feasibility and safety of zero-fluoro, “apron-less” approach to repeat pulmonary vein isolation procedures using radiofrequency energy after initial cryoballoon ablation
title_full_unstemmed Feasibility and safety of zero-fluoro, “apron-less” approach to repeat pulmonary vein isolation procedures using radiofrequency energy after initial cryoballoon ablation
title_short Feasibility and safety of zero-fluoro, “apron-less” approach to repeat pulmonary vein isolation procedures using radiofrequency energy after initial cryoballoon ablation
title_sort feasibility and safety of zero fluoro apron less approach to repeat pulmonary vein isolation procedures using radiofrequency energy after initial cryoballoon ablation
topic Atrial fibrillation
Catheter ablation
Repeat procedures
Zero-fluoroscopy
url https://doi.org/10.1038/s41598-025-87940-6
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