Enhancing Nonenzymatic Glucose Detection Through Cobalt‐Substituted Hafnia

Abstract Engineered defect chemistry in ultrathin (≈5 nm) hafnia through substitutional cobalt (HCO) is investigated for selective glucose sensing. Thin films of HCO, grown using chemical solution deposition (CSD)—traditionally used to grow thick films—on silicon, show significant glucose sensing ac...

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Main Authors: Jeonghyeon Oh, Avis Sin Hui Wee, Eun‐Byeol Park, Jaejin Hwang, Seon Je Kim, Hu Young Jeong, Myat Thet Khine, Pavan Pujar, Jaekwang Lee, Young‐Min Kim, Sunkook Kim
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
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Online Access:https://doi.org/10.1002/advs.202408687
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Summary:Abstract Engineered defect chemistry in ultrathin (≈5 nm) hafnia through substitutional cobalt (HCO) is investigated for selective glucose sensing. Thin films of HCO, grown using chemical solution deposition (CSD)—traditionally used to grow thick films—on silicon, show significant glucose sensing activity and undergo monoclinic to orthorhombic phase transformation. The presence of multivalent cobalt in hafnia, with oxygen vacancies in proximity, selectively oxidizes glucose with minimal interference from ascorbic acid, dopamine, and uric acid. Theoretical investigations reveal that these oxygen vacancies create a shallow donor level that significantly enhances electrocatalytic activity by promoting charge transfer to the conduction band. This results in considerable selectivity, repeatability, and reproducibility in sensing characteristics. These findings highlight the technological importance of using CSD for thin films, paving the way for ultrathin CSD‐processed HCOs as potential candidates for selective glucose sensing applications.
ISSN:2198-3844