Harnessing nanofibers for targeted delivery of phytoconstituents in age-related macular degeneration

Age-related macular degeneration is a degenerative eye condition that affects the macula and results in central vision loss. Phytoconstituents show great promise in the treatment of AMD. AMD therapy can benefit from the advantages of phytoconstituents loaded nanofibers. There are opportunities to im...

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Main Authors: Ulia Andrades, Sahil Gaikar, Khushali Nathani, Sujata Sawarkar, Abdelwahab Omri
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Drug Delivery
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2025.2489491
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author Ulia Andrades
Sahil Gaikar
Khushali Nathani
Sujata Sawarkar
Abdelwahab Omri
author_facet Ulia Andrades
Sahil Gaikar
Khushali Nathani
Sujata Sawarkar
Abdelwahab Omri
author_sort Ulia Andrades
collection DOAJ
description Age-related macular degeneration is a degenerative eye condition that affects the macula and results in central vision loss. Phytoconstituents show great promise in the treatment of AMD. AMD therapy can benefit from the advantages of phytoconstituents loaded nanofibers. There are opportunities to improve the effectiveness of phytoconstituents in the treatment of age-related macular degeneration (AMD) through the use of nanofiber-based delivery methods. These novel platforms encapsulate and distribute plant-derived bioactives by making use of the special qualities of nanofibers. These qualities include their high surface area-to-volume ratio, variable porosity, and biocompatibility. Exploring the use of nanofiber-based delivery methods to provide phytoconstituents in AMD treatment is a great choice for enhancing patient adherence, safety, and efficacy in managing this condition. This article explores the potential of nanofiber-based delivery methods to revolutionize AMD treatment, providing an innovative and effective approach to treat this condition.
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institution OA Journals
issn 1071-7544
1521-0464
language English
publishDate 2025-12-01
publisher Taylor & Francis Group
record_format Article
series Drug Delivery
spelling doaj-art-7a72073b28e94bf0b94494c1b8bcc3092025-08-20T01:53:49ZengTaylor & Francis GroupDrug Delivery1071-75441521-04642025-12-0132110.1080/10717544.2025.2489491Harnessing nanofibers for targeted delivery of phytoconstituents in age-related macular degenerationUlia Andrades0Sahil Gaikar1Khushali Nathani2Sujata Sawarkar3Abdelwahab Omri4Department of Pharmaceutics, SVKM’s Dr. Bhanuben Nanavati College of Pharmacy, University of Mumbai, Mumbai, IndiaDepartment of Pharmaceutics, SVKM’s Dr. Bhanuben Nanavati College of Pharmacy, University of Mumbai, Mumbai, IndiaDepartment of Pharmaceutics, SVKM’s Dr. Bhanuben Nanavati College of Pharmacy, University of Mumbai, Mumbai, IndiaDepartment of Pharmaceutics, SVKM’s Dr. Bhanuben Nanavati College of Pharmacy, University of Mumbai, Mumbai, IndiaThe Novel Drug & Vaccine Delivery Systems Facility, Department of Chemistry and Biochemistry, Laurentian University, Sudbury, ON, CanadaAge-related macular degeneration is a degenerative eye condition that affects the macula and results in central vision loss. Phytoconstituents show great promise in the treatment of AMD. AMD therapy can benefit from the advantages of phytoconstituents loaded nanofibers. There are opportunities to improve the effectiveness of phytoconstituents in the treatment of age-related macular degeneration (AMD) through the use of nanofiber-based delivery methods. These novel platforms encapsulate and distribute plant-derived bioactives by making use of the special qualities of nanofibers. These qualities include their high surface area-to-volume ratio, variable porosity, and biocompatibility. Exploring the use of nanofiber-based delivery methods to provide phytoconstituents in AMD treatment is a great choice for enhancing patient adherence, safety, and efficacy in managing this condition. This article explores the potential of nanofiber-based delivery methods to revolutionize AMD treatment, providing an innovative and effective approach to treat this condition.https://www.tandfonline.com/doi/10.1080/10717544.2025.2489491Age-related macular degenerationnanofiberphytoconstituentsfabricationtargeted delivery
spellingShingle Ulia Andrades
Sahil Gaikar
Khushali Nathani
Sujata Sawarkar
Abdelwahab Omri
Harnessing nanofibers for targeted delivery of phytoconstituents in age-related macular degeneration
Drug Delivery
Age-related macular degeneration
nanofiber
phytoconstituents
fabrication
targeted delivery
title Harnessing nanofibers for targeted delivery of phytoconstituents in age-related macular degeneration
title_full Harnessing nanofibers for targeted delivery of phytoconstituents in age-related macular degeneration
title_fullStr Harnessing nanofibers for targeted delivery of phytoconstituents in age-related macular degeneration
title_full_unstemmed Harnessing nanofibers for targeted delivery of phytoconstituents in age-related macular degeneration
title_short Harnessing nanofibers for targeted delivery of phytoconstituents in age-related macular degeneration
title_sort harnessing nanofibers for targeted delivery of phytoconstituents in age related macular degeneration
topic Age-related macular degeneration
nanofiber
phytoconstituents
fabrication
targeted delivery
url https://www.tandfonline.com/doi/10.1080/10717544.2025.2489491
work_keys_str_mv AT uliaandrades harnessingnanofibersfortargeteddeliveryofphytoconstituentsinagerelatedmaculardegeneration
AT sahilgaikar harnessingnanofibersfortargeteddeliveryofphytoconstituentsinagerelatedmaculardegeneration
AT khushalinathani harnessingnanofibersfortargeteddeliveryofphytoconstituentsinagerelatedmaculardegeneration
AT sujatasawarkar harnessingnanofibersfortargeteddeliveryofphytoconstituentsinagerelatedmaculardegeneration
AT abdelwahabomri harnessingnanofibersfortargeteddeliveryofphytoconstituentsinagerelatedmaculardegeneration