Fluorescent identification of axons, dendrites and soma of neuronal retinal ganglion cells with a genetic marker as a tool for facilitating the study of neurodegeneration

Fluorescent identification of axons, dendrites and soma of neuronal retinal ganglion cells with a genetic marker as a tool for facilitating the study of neurodegeneration

Abstract This study characterizes a fluorescent Slc17a6‐tdTomato neuronal reporter mouse line with strong labeling of axons throughout the optic nerve, of retinal ganglion cell (RGC) soma in the ganglion cell layer (GCL), and of RGC dendrites in the inner plexiform layer (IPL). The model facilitated...

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Bibliographic Details
Main Authors: Puttipong Sripinun, Wennan Lu, Sergei Nikonov, Suhani Patel, Sarah Hennessy, Tianyuan Yao, Qi N. Cui, Brent A. Bell, Claire H. Mitchell
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:FASEB BioAdvances
Subjects:
axons
dendrites
glial/neuron culture
IOP
machine learning
MEA
Online Access:https://doi.org/10.1096/fba.2024-00095
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