Development of a single-dose Q fever vaccine with an injectable nanoparticle-loaded hydrogel: effect of sustained co-delivery of antigen and adjuvant

Development of a single-dose Q fever vaccine with an injectable nanoparticle-loaded hydrogel: effect of sustained co-delivery of antigen and adjuvant

Q fever is a zoonotic infectious disease caused by Coxiella burnetii, and there is currently no FDA-approved vaccine for human use. The whole-cell inactivated vaccine Q-VAX, which is only licensed in Australia, has a risk of causing severe adverse reactions, making subunit vaccines a good alternativ...

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Bibliographic Details
Main Authors: Lu Wang, Aaron Ramirez, Jiin Felgner, Enya Li, Jenny E. Hernandez-Davies, Anthony E. Gregory, Philip L. Felgner, Ali Mohraz, D. Huw Davies, Szu-Wen Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Drug Delivery
Subjects:
Nanoparticle vaccine
hydrogel
co-delivery
sustained delivery
Q fever
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2025.2476144
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