INVESTIGATION OF STRUCTURAL CHARACTERISTICS OF INITIAL SUBSTANCES OF IBUPROFEN AND MICRONIZATION IMPACT

Structural characteristics of ibuprofen substances manufactured by different firms and the impact of micronization on them were compared. The study showed that the use of X-ray diffraction methods was necessary for certification of medicinal (crystalline) since only such methods provided information...

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Main Authors: N. N. Lobanov, N. S. Knuchua, YU. A. Obidenko, R. A. Abramovich
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2020-05-01
Series:Антибиотики и Химиотерапия
Subjects:
Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/425
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author N. N. Lobanov
N. S. Knuchua
YU. A. Obidenko
R. A. Abramovich
author_facet N. N. Lobanov
N. S. Knuchua
YU. A. Obidenko
R. A. Abramovich
author_sort N. N. Lobanov
collection DOAJ
description Structural characteristics of ibuprofen substances manufactured by different firms and the impact of micronization on them were compared. The study showed that the use of X-ray diffraction methods was necessary for certification of medicinal (crystalline) since only such methods provided information on the substance crystal structure, the molecular state and polymorphous forms.
format Article
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institution Kabale University
issn 0235-2990
language Russian
publishDate 2020-05-01
publisher LLC "Publishing House OKI"
record_format Article
series Антибиотики и Химиотерапия
spelling doaj-art-7a61fd4f4b7e41bc809ce2d4aa9b03de2025-08-20T03:59:08ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-01573-438424INVESTIGATION OF STRUCTURAL CHARACTERISTICS OF INITIAL SUBSTANCES OF IBUPROFEN AND MICRONIZATION IMPACTN. N. Lobanov0N. S. Knuchua1YU. A. Obidenko2R. A. Abramovich3Russian University of People FriendshipRussian University of People FriendshipRussian University of People FriendshipRussian University of People FriendshipStructural characteristics of ibuprofen substances manufactured by different firms and the impact of micronization on them were compared. The study showed that the use of X-ray diffraction methods was necessary for certification of medicinal (crystalline) since only such methods provided information on the substance crystal structure, the molecular state and polymorphous forms.https://www.antibiotics-chemotherapy.ru/jour/article/view/425ibuprofensubstancesmicronization
spellingShingle N. N. Lobanov
N. S. Knuchua
YU. A. Obidenko
R. A. Abramovich
INVESTIGATION OF STRUCTURAL CHARACTERISTICS OF INITIAL SUBSTANCES OF IBUPROFEN AND MICRONIZATION IMPACT
Антибиотики и Химиотерапия
ibuprofen
substances
micronization
title INVESTIGATION OF STRUCTURAL CHARACTERISTICS OF INITIAL SUBSTANCES OF IBUPROFEN AND MICRONIZATION IMPACT
title_full INVESTIGATION OF STRUCTURAL CHARACTERISTICS OF INITIAL SUBSTANCES OF IBUPROFEN AND MICRONIZATION IMPACT
title_fullStr INVESTIGATION OF STRUCTURAL CHARACTERISTICS OF INITIAL SUBSTANCES OF IBUPROFEN AND MICRONIZATION IMPACT
title_full_unstemmed INVESTIGATION OF STRUCTURAL CHARACTERISTICS OF INITIAL SUBSTANCES OF IBUPROFEN AND MICRONIZATION IMPACT
title_short INVESTIGATION OF STRUCTURAL CHARACTERISTICS OF INITIAL SUBSTANCES OF IBUPROFEN AND MICRONIZATION IMPACT
title_sort investigation of structural characteristics of initial substances of ibuprofen and micronization impact
topic ibuprofen
substances
micronization
url https://www.antibiotics-chemotherapy.ru/jour/article/view/425
work_keys_str_mv AT nnlobanov investigationofstructuralcharacteristicsofinitialsubstancesofibuprofenandmicronizationimpact
AT nsknuchua investigationofstructuralcharacteristicsofinitialsubstancesofibuprofenandmicronizationimpact
AT yuaobidenko investigationofstructuralcharacteristicsofinitialsubstancesofibuprofenandmicronizationimpact
AT raabramovich investigationofstructuralcharacteristicsofinitialsubstancesofibuprofenandmicronizationimpact