Monounsaturated fatty acids promote cancer radioresistance by inhibiting ferroptosis through ACSL3

Monounsaturated fatty acids promote cancer radioresistance by inhibiting ferroptosis through ACSL3

Abstract Radioresistance is a major challenge in tumor radiotherapy and involves in a mixture of cellular events, including ferroptosis, a new type of programmed cell death characterized by the excess accumulation of iron-dependent lipid peroxides. In the present study, we observed that surviving ca...

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Main Authors: Yulin Cao, Jiuming Li, Ying Chen, Yuanben Wang, Zhiang Liu, Liuying Huang, Bingxin Liu, Yuyang Feng, Surui Yao, Leyuan Zhou, Yuan Yin, Zhaohui Huang
Format: Article
Language:English
Published: Nature Publishing Group 2025-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07516-0
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