5-Fluorouracil Impairs Transmission of Acetylcholine in the Hippocampus and Induces Cognitive Impairments in Mice

5-Fluorouracil Impairs Transmission of Acetylcholine in the Hippocampus and Induces Cognitive Impairments in Mice

Background: Chemotherapy-induced cognitive impairments are a significant adverse sequela of cancer treatment. The potential mechanism of chemotherapy-induced cognitive impairments remains elusive. The present study evaluated the impact of a commonly utilized chemotherapy agent, 5-...

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Bibliographic Details
Main Authors:	Xiwen Huang, Shunqing Peng, Yongquan Lan, Wenjun Chen, Jianlin Wu
Format:	Article
Language:	English
Published:	IMR Press 2025-04-01
Series:	Journal of Integrative Neuroscience
Subjects:	5-fluorouracil acetylcholine cholinergic neurons cognitive impairments medial septum
Online Access:	https://www.imrpress.com/journal/JIN/24/4/10.31083/JIN26903
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