Spontaneous rupture of a giant mature teratoma in the lateral ventricle: a case report

We present the case of an adolescent female patient diagnosed with a ruptured lateral ventricle teratoma. Distinctive radiological and microscopic findings revealed floating oily globules within the ventricles and subarachnoid space. The spontaneous rupture of the teratoma may be attributed to age-d...

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Main Authors: Yong Xiao, Liang Liu, Ran Wang, Dong Wang, Liangyuan Geng, Xinhua Hu, Yong Liu, Chunfa Qian, Yuanjie Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1493982/full
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author Yong Xiao
Liang Liu
Ran Wang
Dong Wang
Liangyuan Geng
Xinhua Hu
Yong Liu
Chunfa Qian
Yuanjie Zou
author_facet Yong Xiao
Liang Liu
Ran Wang
Dong Wang
Liangyuan Geng
Xinhua Hu
Yong Liu
Chunfa Qian
Yuanjie Zou
author_sort Yong Xiao
collection DOAJ
description We present the case of an adolescent female patient diagnosed with a ruptured lateral ventricle teratoma. Distinctive radiological and microscopic findings revealed floating oily globules within the ventricles and subarachnoid space. The spontaneous rupture of the teratoma may be attributed to age-dependent hormonal changes, which increase glandular secretion, cyst content volume, and intra-cystic pressure. The patient underwent gross total resection of the tumor, and the subsequent pathological examination confirmed the diagnosis of mature teratoma. Postoperatively, she was managed with routine follow-up without adjuvant chemotherapy or radiotherapy. During the 1-year follow-up period, the patient remained asymptomatic with no evidence of tumor recurrence. Based on this case, we recommend that gross total resection followed by close monitoring, without adjunctive chemotherapy or radiotherapy, can be an effective treatment strategy for patients with similar presentations.
format Article
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institution Kabale University
issn 2234-943X
language English
publishDate 2025-01-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Oncology
spelling doaj-art-79f94926a12b4abcae9fac5e1bfb29e42025-01-27T06:40:10ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011410.3389/fonc.2024.14939821493982Spontaneous rupture of a giant mature teratoma in the lateral ventricle: a case reportYong XiaoLiang LiuRan WangDong WangLiangyuan GengXinhua HuYong LiuChunfa QianYuanjie ZouWe present the case of an adolescent female patient diagnosed with a ruptured lateral ventricle teratoma. Distinctive radiological and microscopic findings revealed floating oily globules within the ventricles and subarachnoid space. The spontaneous rupture of the teratoma may be attributed to age-dependent hormonal changes, which increase glandular secretion, cyst content volume, and intra-cystic pressure. The patient underwent gross total resection of the tumor, and the subsequent pathological examination confirmed the diagnosis of mature teratoma. Postoperatively, she was managed with routine follow-up without adjuvant chemotherapy or radiotherapy. During the 1-year follow-up period, the patient remained asymptomatic with no evidence of tumor recurrence. Based on this case, we recommend that gross total resection followed by close monitoring, without adjunctive chemotherapy or radiotherapy, can be an effective treatment strategy for patients with similar presentations.https://www.frontiersin.org/articles/10.3389/fonc.2024.1493982/fullgiant teratomarupturethe lateral ventricleadolescent femalecase report
spellingShingle Yong Xiao
Liang Liu
Ran Wang
Dong Wang
Liangyuan Geng
Xinhua Hu
Yong Liu
Chunfa Qian
Yuanjie Zou
Spontaneous rupture of a giant mature teratoma in the lateral ventricle: a case report
Frontiers in Oncology
giant teratoma
rupture
the lateral ventricle
adolescent female
case report
title Spontaneous rupture of a giant mature teratoma in the lateral ventricle: a case report
title_full Spontaneous rupture of a giant mature teratoma in the lateral ventricle: a case report
title_fullStr Spontaneous rupture of a giant mature teratoma in the lateral ventricle: a case report
title_full_unstemmed Spontaneous rupture of a giant mature teratoma in the lateral ventricle: a case report
title_short Spontaneous rupture of a giant mature teratoma in the lateral ventricle: a case report
title_sort spontaneous rupture of a giant mature teratoma in the lateral ventricle a case report
topic giant teratoma
rupture
the lateral ventricle
adolescent female
case report
url https://www.frontiersin.org/articles/10.3389/fonc.2024.1493982/full
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