Group Contribution Revisited: The Enthalpy of Formation of Organic Compounds with “Chemical Accuracy” Part VI

In this paper we provide the reader with a ready to use Group Contribution (GC) method for the heat of formation (gaseous state) of organics in the form of an Excel spreadsheet with all data, enabling further predictions, and an accompanying manual on how to use the GC model for predicting the heat...

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Main Authors: Robert J. Meier, Paul R. Rablen
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:AppliedChem
Subjects:
Online Access:https://www.mdpi.com/2673-9623/4/4/21
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author Robert J. Meier
Paul R. Rablen
author_facet Robert J. Meier
Paul R. Rablen
author_sort Robert J. Meier
collection DOAJ
description In this paper we provide the reader with a ready to use Group Contribution (GC) method for the heat of formation (gaseous state) of organics in the form of an Excel spreadsheet with all data, enabling further predictions, and an accompanying manual on how to use the GC model for predicting the heat of formation for organics. In addition, in order to widen the applicability of the method whilst retaining chemical accuracy compared to our previous publications on this topic, we include further chemical groups including acetals, benzyl ethers, bicyclic hydrocarbons, alkanediols and glycerol, polycyclic aromatic hydrocarbons, aromatic fluoro compounds, and finally several species which we include to illustrate how the GC model can be successfully applied to species we did not consider during the parameterization of the GC model parameters.
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spelling doaj-art-79f25d962de14eb9bca3b811b488983a2024-12-27T14:07:06ZengMDPI AGAppliedChem2673-96232024-10-014433335210.3390/appliedchem4040021Group Contribution Revisited: The Enthalpy of Formation of Organic Compounds with “Chemical Accuracy” Part VIRobert J. Meier0Paul R. Rablen1Pro-Deo Consultant, 52525 Heinsberg, North-Rhine Westphalia, GermanyDepartment of Chemistry and Biochemistry, Swarthmore College, Swarthmore, PA 19081, USAIn this paper we provide the reader with a ready to use Group Contribution (GC) method for the heat of formation (gaseous state) of organics in the form of an Excel spreadsheet with all data, enabling further predictions, and an accompanying manual on how to use the GC model for predicting the heat of formation for organics. In addition, in order to widen the applicability of the method whilst retaining chemical accuracy compared to our previous publications on this topic, we include further chemical groups including acetals, benzyl ethers, bicyclic hydrocarbons, alkanediols and glycerol, polycyclic aromatic hydrocarbons, aromatic fluoro compounds, and finally several species which we include to illustrate how the GC model can be successfully applied to species we did not consider during the parameterization of the GC model parameters.https://www.mdpi.com/2673-9623/4/4/21enthalpy of formationreaction enthalpythermodynamicsprocess designphysicochemical property predictiongroup contribution method
spellingShingle Robert J. Meier
Paul R. Rablen
Group Contribution Revisited: The Enthalpy of Formation of Organic Compounds with “Chemical Accuracy” Part VI
AppliedChem
enthalpy of formation
reaction enthalpy
thermodynamics
process design
physicochemical property prediction
group contribution method
title Group Contribution Revisited: The Enthalpy of Formation of Organic Compounds with “Chemical Accuracy” Part VI
title_full Group Contribution Revisited: The Enthalpy of Formation of Organic Compounds with “Chemical Accuracy” Part VI
title_fullStr Group Contribution Revisited: The Enthalpy of Formation of Organic Compounds with “Chemical Accuracy” Part VI
title_full_unstemmed Group Contribution Revisited: The Enthalpy of Formation of Organic Compounds with “Chemical Accuracy” Part VI
title_short Group Contribution Revisited: The Enthalpy of Formation of Organic Compounds with “Chemical Accuracy” Part VI
title_sort group contribution revisited the enthalpy of formation of organic compounds with chemical accuracy part vi
topic enthalpy of formation
reaction enthalpy
thermodynamics
process design
physicochemical property prediction
group contribution method
url https://www.mdpi.com/2673-9623/4/4/21
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