Structure of SALO, a leishmaniasis vaccine candidate from the sand fly Lutzomyia longipalpis.

Structure of SALO, a leishmaniasis vaccine candidate from the sand fly Lutzomyia longipalpis.

<h4>Background</h4>Immunity to the sand fly salivary protein SALO (Salivary Anticomplement of Lutzomyia longipalpis) protected hamsters against Leishmania infantum and L. braziliensis infection and, more recently, a vaccine combination of a genetically modified Leishmania with SALO confe...

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Main Authors: Oluwatoyin A Asojo, Alan Kelleher, Zhuyun Liu, Jeroen Pollet, Elissa M Hudspeth, Wanderson C Rezende, Mallory Jo Groen, Christopher A Seid, Maha Abdeladhim, Shannon Townsend, Waldione de Castro, Antonio Mendes-Sousa, Daniella Castanheira Bartholomeu, Ricardo Toshio Fujiwara, Maria Elena Bottazzi, Peter J Hotez, Bin Zhan, Fabiano Oliveira, Shaden Kamhawi, Jesus G Valenzuela
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0005374&type=printable
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