Fusobacterium necrophorum associated with pelvic infections: A case series and literature review

Fusobacterium necrophorum is a gram-negative anaerobic bacillus most commonly implicated in oropharyngeal infections and their subsequent complications, including septic thrombophlebitis of the internal jugular vein, or Lemierre syndrome. However, limited case reports document evidence of pelvic inf...

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Main Authors: Manasa Brown, Sabrina Imam, Jade Pagkas-Bather
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:IDCases
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214250925000459
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author Manasa Brown
Sabrina Imam
Jade Pagkas-Bather
author_facet Manasa Brown
Sabrina Imam
Jade Pagkas-Bather
author_sort Manasa Brown
collection DOAJ
description Fusobacterium necrophorum is a gram-negative anaerobic bacillus most commonly implicated in oropharyngeal infections and their subsequent complications, including septic thrombophlebitis of the internal jugular vein, or Lemierre syndrome. However, limited case reports document evidence of pelvic infections associated with Fusobacterium as well, such as pelvic peritonitis and pelvic septic vein thrombophlebitis. In this case series, we discuss two occurrences of Fusobacterium necrophorum bacteremia from a presumed gynecologic source and present a literature review of other reported cases of Fusobacterium associated with female pelvic etiology. While current data describe a greater prevalence of Fusobacterium infections overall in men compared to women, more information is needed regarding the clinical significance of female-specific risk factors that may predispose to this disease.
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spelling doaj-art-79f0e466efcc424ab86de82f16b90afa2025-08-20T02:06:22ZengElsevierIDCases2214-25092025-01-0139e0219010.1016/j.idcr.2025.e02190Fusobacterium necrophorum associated with pelvic infections: A case series and literature reviewManasa Brown0Sabrina Imam1Jade Pagkas-Bather2Department of Medicine, University of Chicago, Chicago, IL, USA; Correspondence to: Department of Medicine, University of Chicago, 5841 South Maryland Ave, MC 6092, Chicago, IL 60637, USA.Section of Infectious Diseases and Global Health, University of Chicago, Chicago, IL, USASection of Infectious Diseases and Global Health, University of Chicago, Chicago, IL, USAFusobacterium necrophorum is a gram-negative anaerobic bacillus most commonly implicated in oropharyngeal infections and their subsequent complications, including septic thrombophlebitis of the internal jugular vein, or Lemierre syndrome. However, limited case reports document evidence of pelvic infections associated with Fusobacterium as well, such as pelvic peritonitis and pelvic septic vein thrombophlebitis. In this case series, we discuss two occurrences of Fusobacterium necrophorum bacteremia from a presumed gynecologic source and present a literature review of other reported cases of Fusobacterium associated with female pelvic etiology. While current data describe a greater prevalence of Fusobacterium infections overall in men compared to women, more information is needed regarding the clinical significance of female-specific risk factors that may predispose to this disease.http://www.sciencedirect.com/science/article/pii/S2214250925000459Fusobacterium necrophorumPelvic infectionsAnaerobic bacteremia
spellingShingle Manasa Brown
Sabrina Imam
Jade Pagkas-Bather
Fusobacterium necrophorum associated with pelvic infections: A case series and literature review
IDCases
Fusobacterium necrophorum
Pelvic infections
Anaerobic bacteremia
title Fusobacterium necrophorum associated with pelvic infections: A case series and literature review
title_full Fusobacterium necrophorum associated with pelvic infections: A case series and literature review
title_fullStr Fusobacterium necrophorum associated with pelvic infections: A case series and literature review
title_full_unstemmed Fusobacterium necrophorum associated with pelvic infections: A case series and literature review
title_short Fusobacterium necrophorum associated with pelvic infections: A case series and literature review
title_sort fusobacterium necrophorum associated with pelvic infections a case series and literature review
topic Fusobacterium necrophorum
Pelvic infections
Anaerobic bacteremia
url http://www.sciencedirect.com/science/article/pii/S2214250925000459
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