Seroprevalence of Canine Leishmaniasis in Sheltered Dogs in Bushehr Province, Southwest of Iran during 2022-2023
Background: The Mediterranean form of visceral leishmaniasis (VL) is endemic in some regions of Iran and is often seen in children under 10 years old. There is a 90% mortality in patients, if diagnosis and treatment are not done on time. Canids, as reservoirs, play an important role in the spread o...
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Tehran University of Medical Sciences
2025-06-01
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| Series: | Iranian Journal of Parasitology |
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| Online Access: | https://ijpa.tums.ac.ir/index.php/ijpa/article/view/4293 |
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| author | Negar Zare Abdollah Najm Mehdi Mohebali Alireza Sahebani Mohammad Rayani Zabihollah Zareei Maryam Bemana Afshin Barazesh |
| author_facet | Negar Zare Abdollah Najm Mehdi Mohebali Alireza Sahebani Mohammad Rayani Zabihollah Zareei Maryam Bemana Afshin Barazesh |
| author_sort | Negar Zare |
| collection | DOAJ |
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Background: The Mediterranean form of visceral leishmaniasis (VL) is endemic in some regions of Iran and is often seen in children under 10 years old. There is a 90% mortality in patients, if diagnosis and treatment are not done on time. Canids, as reservoirs, play an important role in the spread of the disease.
Methods: Bushehr Province, southern Iran is always mentioned as one of the endemic areas for VL, so for this purpose, as the first study in the region, 112 sheltered dogs in Bushehr City were evaluated for canine leishmaniasis (CanL) using serological Direct Agglutination Test (DAT) as well as detailed clinical examinations.
Results: Out of 112 samples collected, 71.4% of cases had anti-L. infantum IgG antibody titers of 1:80 and higher and therefore considered as seropositive. Furthermore, from the 70 seropositive dogs with antibody titer of 1:320 and higher, 47 (42%) had at least one of the clinical symptoms associated with VL and considered as cases with CanL.
Conclusion: The current seroprevalence situation of dogs in this region, is very noticeable and can be an important alarm for policymakers and health system practitioners. More comprehensive and complementary parasitological studies should be carried out on a number of reservoirs in the region for diagnosis and treatment and to accurately determine the statistics of the disease compared to the obtained seroprevalence status.
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| format | Article |
| id | doaj-art-79e7bcc32b5347e9b1539c16d0a363bb |
| institution | Kabale University |
| issn | 1735-7020 2008-238X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Parasitology |
| spelling | doaj-art-79e7bcc32b5347e9b1539c16d0a363bb2025-08-20T03:29:09ZengTehran University of Medical SciencesIranian Journal of Parasitology1735-70202008-238X2025-06-0120210.18502/ijpa.v20i2.19047Seroprevalence of Canine Leishmaniasis in Sheltered Dogs in Bushehr Province, Southwest of Iran during 2022-2023Negar Zare0Abdollah Najm1Mehdi Mohebali2Alireza Sahebani3Mohammad Rayani4Zabihollah Zareei5Maryam Bemana6Afshin Barazesh7Student Research and Technology Committee, Bushehr University of Medical Sciences, Bushehr, IranBushehr Veterinary Organization, Bushehr, IranDepartment of Medical Parasitology and Mycology, School of Health, Tehran University of Medical Sciences, Tehran, IranStudent Research and Technology Committee, Bushehr University of Medical Sciences, Bushehr, IranDepartment of Microbiology & Parasitology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, IranDepartment of Medical Parasitology and Mycology, School of Health, Tehran University of Medical Sciences, Tehran, IranStudent Research and Technology Committee, Bushehr University of Medical Sciences, Bushehr, IranDepartment of Microbiology & Parasitology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran Background: The Mediterranean form of visceral leishmaniasis (VL) is endemic in some regions of Iran and is often seen in children under 10 years old. There is a 90% mortality in patients, if diagnosis and treatment are not done on time. Canids, as reservoirs, play an important role in the spread of the disease. Methods: Bushehr Province, southern Iran is always mentioned as one of the endemic areas for VL, so for this purpose, as the first study in the region, 112 sheltered dogs in Bushehr City were evaluated for canine leishmaniasis (CanL) using serological Direct Agglutination Test (DAT) as well as detailed clinical examinations. Results: Out of 112 samples collected, 71.4% of cases had anti-L. infantum IgG antibody titers of 1:80 and higher and therefore considered as seropositive. Furthermore, from the 70 seropositive dogs with antibody titer of 1:320 and higher, 47 (42%) had at least one of the clinical symptoms associated with VL and considered as cases with CanL. Conclusion: The current seroprevalence situation of dogs in this region, is very noticeable and can be an important alarm for policymakers and health system practitioners. More comprehensive and complementary parasitological studies should be carried out on a number of reservoirs in the region for diagnosis and treatment and to accurately determine the statistics of the disease compared to the obtained seroprevalence status. https://ijpa.tums.ac.ir/index.php/ijpa/article/view/4293Visceral leishmaniasisSheltered dogsIran |
| spellingShingle | Negar Zare Abdollah Najm Mehdi Mohebali Alireza Sahebani Mohammad Rayani Zabihollah Zareei Maryam Bemana Afshin Barazesh Seroprevalence of Canine Leishmaniasis in Sheltered Dogs in Bushehr Province, Southwest of Iran during 2022-2023 Iranian Journal of Parasitology Visceral leishmaniasis Sheltered dogs Iran |
| title | Seroprevalence of Canine Leishmaniasis in Sheltered Dogs in Bushehr Province, Southwest of Iran during 2022-2023 |
| title_full | Seroprevalence of Canine Leishmaniasis in Sheltered Dogs in Bushehr Province, Southwest of Iran during 2022-2023 |
| title_fullStr | Seroprevalence of Canine Leishmaniasis in Sheltered Dogs in Bushehr Province, Southwest of Iran during 2022-2023 |
| title_full_unstemmed | Seroprevalence of Canine Leishmaniasis in Sheltered Dogs in Bushehr Province, Southwest of Iran during 2022-2023 |
| title_short | Seroprevalence of Canine Leishmaniasis in Sheltered Dogs in Bushehr Province, Southwest of Iran during 2022-2023 |
| title_sort | seroprevalence of canine leishmaniasis in sheltered dogs in bushehr province southwest of iran during 2022 2023 |
| topic | Visceral leishmaniasis Sheltered dogs Iran |
| url | https://ijpa.tums.ac.ir/index.php/ijpa/article/view/4293 |
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