Optimization of PLA/Mg/PEG biocomposite filaments for 3D-printed bone scaffolds using response surface methodology (RSM)
This study optimizes biocomposite filaments composed of polylactic acid (PLA), magnesium (Mg), and polyethylene glycol (PEG) for bone scaffold applications via 3D printing. Using Response Surface Methodology, extrusion parameters including temperature, screw speed, and Mg and PEG proportions were op...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Advanced Manufacturing: Polymer & Composites Science |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/20550340.2024.2448648 |
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| author | Imam Akbar Hasan Basri Muhammad Yanis Muhammad Imam Ammarullah |
| author_facet | Imam Akbar Hasan Basri Muhammad Yanis Muhammad Imam Ammarullah |
| author_sort | Imam Akbar |
| collection | DOAJ |
| description | This study optimizes biocomposite filaments composed of polylactic acid (PLA), magnesium (Mg), and polyethylene glycol (PEG) for bone scaffold applications via 3D printing. Using Response Surface Methodology, extrusion parameters including temperature, screw speed, and Mg and PEG proportions were optimized to achieve a consistent filament diameter of 1.75 mm, meeting 3D printing standards. Extrusion temperature significantly influenced filament diameter by reducing PLA viscosity at higher temperatures. Screw speed impacted diameter uniformity and density, while Mg enhanced filament strength but posed challenges in uniform distribution. PEG improved flexibility, mitigating Mg-induced stiffness. Scanning electron microscopy revealed voids and uneven Mg inclusions, indicating areas for process enhancement. These findings advance the development of optimized biocomposite filaments, providing a foundation for improved fabrication techniques in bone tissue engineering. |
| format | Article |
| id | doaj-art-79e4aaa3eae44b6d9ee33ea6291703ad |
| institution | OA Journals |
| issn | 2055-0340 2055-0359 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Advanced Manufacturing: Polymer & Composites Science |
| spelling | doaj-art-79e4aaa3eae44b6d9ee33ea6291703ad2025-08-20T02:27:19ZengTaylor & Francis GroupAdvanced Manufacturing: Polymer & Composites Science2055-03402055-03592025-12-0111110.1080/20550340.2024.2448648Optimization of PLA/Mg/PEG biocomposite filaments for 3D-printed bone scaffolds using response surface methodology (RSM)Imam Akbar0Hasan Basri1Muhammad Yanis2Muhammad Imam Ammarullah3Doctoral Program Study of Engineering Science, Faculty of Engineering, Universitas Sriwijaya, Palembang, South Sumatera, IndonesiaDepartment of Mechanical Engineering, Faculty of Engineering, Universitas Sriwijaya, Indralaya, South Sumatera, IndonesiaDepartment of Mechanical Engineering, Faculty of Engineering, Universitas Sriwijaya, Indralaya, South Sumatera, IndonesiaDepartment of Mechanical Engineering, Faculty of Engineering, Universitas Diponegoro, Semarang, Central Java, IndonesiaThis study optimizes biocomposite filaments composed of polylactic acid (PLA), magnesium (Mg), and polyethylene glycol (PEG) for bone scaffold applications via 3D printing. Using Response Surface Methodology, extrusion parameters including temperature, screw speed, and Mg and PEG proportions were optimized to achieve a consistent filament diameter of 1.75 mm, meeting 3D printing standards. Extrusion temperature significantly influenced filament diameter by reducing PLA viscosity at higher temperatures. Screw speed impacted diameter uniformity and density, while Mg enhanced filament strength but posed challenges in uniform distribution. PEG improved flexibility, mitigating Mg-induced stiffness. Scanning electron microscopy revealed voids and uneven Mg inclusions, indicating areas for process enhancement. These findings advance the development of optimized biocomposite filaments, providing a foundation for improved fabrication techniques in bone tissue engineering.https://www.tandfonline.com/doi/10.1080/20550340.2024.2448648PLAMgPEGbiocompositefilamentresponse surface methodology |
| spellingShingle | Imam Akbar Hasan Basri Muhammad Yanis Muhammad Imam Ammarullah Optimization of PLA/Mg/PEG biocomposite filaments for 3D-printed bone scaffolds using response surface methodology (RSM) Advanced Manufacturing: Polymer & Composites Science PLA Mg PEG biocomposite filament response surface methodology |
| title | Optimization of PLA/Mg/PEG biocomposite filaments for 3D-printed bone scaffolds using response surface methodology (RSM) |
| title_full | Optimization of PLA/Mg/PEG biocomposite filaments for 3D-printed bone scaffolds using response surface methodology (RSM) |
| title_fullStr | Optimization of PLA/Mg/PEG biocomposite filaments for 3D-printed bone scaffolds using response surface methodology (RSM) |
| title_full_unstemmed | Optimization of PLA/Mg/PEG biocomposite filaments for 3D-printed bone scaffolds using response surface methodology (RSM) |
| title_short | Optimization of PLA/Mg/PEG biocomposite filaments for 3D-printed bone scaffolds using response surface methodology (RSM) |
| title_sort | optimization of pla mg peg biocomposite filaments for 3d printed bone scaffolds using response surface methodology rsm |
| topic | PLA Mg PEG biocomposite filament response surface methodology |
| url | https://www.tandfonline.com/doi/10.1080/20550340.2024.2448648 |
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