Treatment of Enteropathogenic Escherichia coli Diarrhea in Cancer Patients: A Series of Three Cases

Enteropathogenic Escherichia coli (EPEC) is a common cause of watery diarrhea in children in the developing world and an infrequent cause of significant diarrhea in adult patients. EPEC diarrhea, while not commonly seen in cancer patients, can cause significant distress to patients, and antimicrobia...

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Main Authors: James D. Denham, Sowmya Nanjappa, John N. Greene
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2018/8438701
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author James D. Denham
Sowmya Nanjappa
John N. Greene
author_facet James D. Denham
Sowmya Nanjappa
John N. Greene
author_sort James D. Denham
collection DOAJ
description Enteropathogenic Escherichia coli (EPEC) is a common cause of watery diarrhea in children in the developing world and an infrequent cause of significant diarrhea in adult patients. EPEC diarrhea, while not commonly seen in cancer patients, can cause significant distress to patients, and antimicrobial choice for this condition in this patient population is not clearly delineated in the literature. We report 3 cases of EPEC diarrhea in cancer patients and discuss the use of azithromycin for successful treatment of these patients. Positive outcomes were seen while using azithromycin in our first two patients and ciprofloxacin in our third patient.
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spelling doaj-art-79cf254f2beb4639ae226a206984ef9c2025-08-20T03:35:46ZengWileyCase Reports in Infectious Diseases2090-66252090-66332018-01-01201810.1155/2018/84387018438701Treatment of Enteropathogenic Escherichia coli Diarrhea in Cancer Patients: A Series of Three CasesJames D. Denham0Sowmya Nanjappa1John N. Greene2University of South Florida Morsani College of Medicine, 12901 Bruce B. Downs Blvd., Tampa, FL 33612, USADepartment of Internal Medicine and Oncologic Sciences, H. Lee Moffitt Cancer Center, University of South Florida Morsani College of Medicine, 12902 Magnolia Drive, MCC-IHM, Tampa, FL 33612-9497, USAInfectious Diseases and Hospital Epidemiology, Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, FOB-3, Tampa, FL 33612-9497, USAEnteropathogenic Escherichia coli (EPEC) is a common cause of watery diarrhea in children in the developing world and an infrequent cause of significant diarrhea in adult patients. EPEC diarrhea, while not commonly seen in cancer patients, can cause significant distress to patients, and antimicrobial choice for this condition in this patient population is not clearly delineated in the literature. We report 3 cases of EPEC diarrhea in cancer patients and discuss the use of azithromycin for successful treatment of these patients. Positive outcomes were seen while using azithromycin in our first two patients and ciprofloxacin in our third patient.http://dx.doi.org/10.1155/2018/8438701
spellingShingle James D. Denham
Sowmya Nanjappa
John N. Greene
Treatment of Enteropathogenic Escherichia coli Diarrhea in Cancer Patients: A Series of Three Cases
Case Reports in Infectious Diseases
title Treatment of Enteropathogenic Escherichia coli Diarrhea in Cancer Patients: A Series of Three Cases
title_full Treatment of Enteropathogenic Escherichia coli Diarrhea in Cancer Patients: A Series of Three Cases
title_fullStr Treatment of Enteropathogenic Escherichia coli Diarrhea in Cancer Patients: A Series of Three Cases
title_full_unstemmed Treatment of Enteropathogenic Escherichia coli Diarrhea in Cancer Patients: A Series of Three Cases
title_short Treatment of Enteropathogenic Escherichia coli Diarrhea in Cancer Patients: A Series of Three Cases
title_sort treatment of enteropathogenic escherichia coli diarrhea in cancer patients a series of three cases
url http://dx.doi.org/10.1155/2018/8438701
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