Irritation Assessment of Herbal Deodorant from Essential Oil of Pomelo (Citrus maxima) Peel on Rabbit Skin
A deodorant manages an unpleasant body odor through both reducing and suppressing antibacterial activity and it is formulated generally using antibacterial agents and fragrances. Nowadays, quaternary ammonium compounds like triclosan, aluminum salts, and odor eliminators are used as antibacterial ag...
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| Format: | Article |
| Language: | English |
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LPPT Universitas Gadjah Mada
2024-12-01
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| Series: | Journal of Food and Pharmaceutical Sciences |
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| Online Access: | https://jurnal.ugm.ac.id/v3/JFPS/article/view/12139/5273 |
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| author | Wisdawati Wisdawati Selpida Handayani Mamat Pratama |
| author_facet | Wisdawati Wisdawati Selpida Handayani Mamat Pratama |
| author_sort | Wisdawati Wisdawati |
| collection | DOAJ |
| description | A deodorant manages an unpleasant body odor through both reducing and suppressing antibacterial activity and it is formulated generally using antibacterial agents and fragrances. Nowadays, quaternary ammonium compounds like triclosan, aluminum salts, and odor eliminators are used as antibacterial agents and fragrance in deodorant products. A nature-based deodorant potentially replace the synthetic deodorant with less irritating effect. Pomelo (Citrus maxima) is one of the Indonesian plants which has some bioactive compounds, including limonene. Essential oil of Pomelo peel (EOPP) exhibits an antibacterial activity as well as fragrance. The aim of this research is to observe the irritation effect of EOPP deodorant on rabbit skin. The irritation assay of herbal deodorant of EOPP with various concentrations (F1: 1.25%; F2: 2.5% and F3: 5%) was carried out based on protocol for dermal acute irritation test on rabbit skin. All the formulations performed the same grades (negligible criteria) with the irritation index of F1, F2 and F3: 0; 0.037 and 0.148, respectively. The herbal deodorants with various concentrations of EOPP did not show an irritating effect on rabbit skin. |
| format | Article |
| id | doaj-art-79c5920ac27d421180ae714de488d1bf |
| institution | Kabale University |
| issn | 2089-7200 2339-0948 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | LPPT Universitas Gadjah Mada |
| record_format | Article |
| series | Journal of Food and Pharmaceutical Sciences |
| spelling | doaj-art-79c5920ac27d421180ae714de488d1bf2025-01-24T10:09:09ZengLPPT Universitas Gadjah MadaJournal of Food and Pharmaceutical Sciences2089-72002339-09482024-12-0112319820410.22146/jfps.12139Irritation Assessment of Herbal Deodorant from Essential Oil of Pomelo (Citrus maxima) Peel on Rabbit SkinWisdawati Wisdawati0Selpida Handayani1Mamat Pratama2Department of Pharmacognosy-Phytochemistry, Universitas Muslim Indonesia, Makassar, South Sulawesi, IndonesiaDepartment of Pharmacognosy-Phytochemistry, Universitas Muslim Indonesia, Makassar, South Sulawesi, IndonesiaDepartmentof Pharmaceutical Chemistry, Universitas Muslim Indonesia, Makassar, South Sulawesi, IndonesiaA deodorant manages an unpleasant body odor through both reducing and suppressing antibacterial activity and it is formulated generally using antibacterial agents and fragrances. Nowadays, quaternary ammonium compounds like triclosan, aluminum salts, and odor eliminators are used as antibacterial agents and fragrance in deodorant products. A nature-based deodorant potentially replace the synthetic deodorant with less irritating effect. Pomelo (Citrus maxima) is one of the Indonesian plants which has some bioactive compounds, including limonene. Essential oil of Pomelo peel (EOPP) exhibits an antibacterial activity as well as fragrance. The aim of this research is to observe the irritation effect of EOPP deodorant on rabbit skin. The irritation assay of herbal deodorant of EOPP with various concentrations (F1: 1.25%; F2: 2.5% and F3: 5%) was carried out based on protocol for dermal acute irritation test on rabbit skin. All the formulations performed the same grades (negligible criteria) with the irritation index of F1, F2 and F3: 0; 0.037 and 0.148, respectively. The herbal deodorants with various concentrations of EOPP did not show an irritating effect on rabbit skin.https://jurnal.ugm.ac.id/v3/JFPS/article/view/12139/5273body odorherbal deodorantessential oilskin irritationpomelo peelcitrus maxima |
| spellingShingle | Wisdawati Wisdawati Selpida Handayani Mamat Pratama Irritation Assessment of Herbal Deodorant from Essential Oil of Pomelo (Citrus maxima) Peel on Rabbit Skin Journal of Food and Pharmaceutical Sciences body odor herbal deodorant essential oil skin irritation pomelo peel citrus maxima |
| title | Irritation Assessment of Herbal Deodorant from Essential Oil of Pomelo (Citrus maxima) Peel on Rabbit Skin |
| title_full | Irritation Assessment of Herbal Deodorant from Essential Oil of Pomelo (Citrus maxima) Peel on Rabbit Skin |
| title_fullStr | Irritation Assessment of Herbal Deodorant from Essential Oil of Pomelo (Citrus maxima) Peel on Rabbit Skin |
| title_full_unstemmed | Irritation Assessment of Herbal Deodorant from Essential Oil of Pomelo (Citrus maxima) Peel on Rabbit Skin |
| title_short | Irritation Assessment of Herbal Deodorant from Essential Oil of Pomelo (Citrus maxima) Peel on Rabbit Skin |
| title_sort | irritation assessment of herbal deodorant from essential oil of pomelo citrus maxima peel on rabbit skin |
| topic | body odor herbal deodorant essential oil skin irritation pomelo peel citrus maxima |
| url | https://jurnal.ugm.ac.id/v3/JFPS/article/view/12139/5273 |
| work_keys_str_mv | AT wisdawatiwisdawati irritationassessmentofherbaldeodorantfromessentialoilofpomelocitrusmaximapeelonrabbitskin AT selpidahandayani irritationassessmentofherbaldeodorantfromessentialoilofpomelocitrusmaximapeelonrabbitskin AT mamatpratama irritationassessmentofherbaldeodorantfromessentialoilofpomelocitrusmaximapeelonrabbitskin |