Oral administration of Momordica charantia-derived extracellular vesicles alleviates ulcerative colitis through comprehensive renovation of the intestinal microenvironment
Abstract Background Ulcerative colitis (UC) is an inflammatory bowel disease (IBD), accompanied by intense inflammation, oxidative stress, and intestinal microbiota dysbiosis. Current treatments using chemotherapeutic drugs or immunosuppressants have limited effectiveness and side effects. Therefore...
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| Main Authors: | Bowen Gao, Xiaoling Huang, Junlong Fu, Liyuan Chen, Zhichao Deng, Shuhui Wang, Yuanyuan Zhu, Chenxi Xu, Yujie Zhang, Mingxin Zhang, Lina Chen, Manli Cui, Mingzhen Zhang |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-04-01
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| Series: | Journal of Nanobiotechnology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12951-025-03346-6 |
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