Integrated multiomics approach and pathological analyses provide new insights into hepatic injury and metabolic alterations in Saanen goats after dietary exposure to aflatoxin B1

Integrated multiomics approach and pathological analyses provide new insights into hepatic injury and metabolic alterations in Saanen goats after dietary exposure to aflatoxin B1

ABSTRACT: Exploring the toxicity and metabolic mechanisms of aflatoxin B1 (AFB1) in ruminants can help to develop strategies to prevent or reduce the transfer of the toxin and its metabolites to milk and meat. This study aimed to explore the effects of 3 concentrations of dietary AFB1 (0, 50, and 50...

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Bibliographic Details
Main Authors: Donghua Su, Jing Peng, Jingjing Hao, Xi Wang, Peiqiang Yu, Shengli Li, Haitao Shi
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of Dairy Science
Subjects:
aflatoxin B1
hepatocyte apoptosis
transcriptome
metabolome
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030224012499
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