Efficacy of febuxostat on hyperuricemia and estimated glomerular filtration rate in patients with non-dialysis stage 3/4 chronic kidney disease and assessment of cardiac function: a 12-month interventional study

Efficacy of febuxostat on hyperuricemia and estimated glomerular filtration rate in patients with non-dialysis stage 3/4 chronic kidney disease and assessment of cardiac function: a 12-month interventional study

ObjectivesFebuxostat, an oral medication for treating hyperuricemia (HUA), is a non-purine xanthine oxidase inhibitor that regulates serum uric acid (SUA) metabolism in patients with chronic kidney disease (CKD). However, the drug’s effectiveness in improving renal function in patients with non-dial...

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Bibliographic Details
Main Authors: Yousuf Abdulkarim Waheed, Fan Yang, Jie Liu, Shifaa Almayahe, Karthick Kumaran Munisamy Selvam, Disheng Wang, Dong Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Nephrology
Subjects:
febuxostat
hyperuricemia
chronic kidney disease
cardiovascular
troponin
Online Access:https://www.frontiersin.org/articles/10.3389/fneph.2025.1526182/full
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