Personalized brain functional sectors guided theta burst transcranial magnetic stimulation for treatment-resistant depression: a study protocol for a multi-centre, randomised, double-blind, sham-controlled clinical trial

Personalized brain functional sectors guided theta burst transcranial magnetic stimulation for treatment-resistant depression: a study protocol for a multi-centre, randomised, double-blind, sham-controlled clinical trial

Introduction Depression is characterised by disruptions in brain circuitry, and interventions like intermittent theta burst stimulation (iTBS) offer the potential for normalising these circuits and improving clinical symptoms. However, personalised treatment targets for depression remain underexplor...

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Main Authors: Ling Zhang, Ping Zhang, Wuxiang Xie, Hao Cheng, Kai Wang, Yongbo Hu, Qiyong Gong, Weihong Kuang, Meiyun Wang, Gang Wang, Liang Li, Wen Qin, Weihua Yue, Dai Zhang, Lijuan Chen, Gongjun Ji, Hesheng Liu, Meiling Li, Chunshui Yu, Ziqiang Li, Yuyanan Zhang, Yansheng Jiang, Sixiang Liang, Xiaoyue Sun, Zekun Yang
Format: Article
Language:English
Published: BMJ Publishing Group 2025-07-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/7/e098155.full
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