iNKT Cell Activation Exacerbates the Development of Huntington’s Disease in R6/2 Transgenic Mice

Huntington’s disease (HD) is an inherited neurodegenerative disorder which is caused by a mutation of the huntingtin (HTT) gene. Although the pathogenesis of HD has been associated with inflammatory responses, if and how the immune system contributes to the onset of HD is largely unknown. Invariant...

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Bibliographic Details
Main Authors: Hyun Jung Park, Sung Won Lee, Wooseok Im, Manho Kim, Luc Van Kaer, Seokmann Hong
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2019/3540974
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