NUP62 alleviates senescence and promotes the stemness of human dental pulp stem cells via NSD2-dependent epigenetic reprogramming

NUP62 alleviates senescence and promotes the stemness of human dental pulp stem cells via NSD2-dependent epigenetic reprogramming

Abstract Stem cells play a crucial role in maintaining tissue regenerative capacity and homeostasis. However, mechanisms associated with stem cell senescence require further investigation. In this study, we conducted a proteomic analysis of human dental pulp stem cells (HDPSCs) obtained from individ...

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Main Authors: Xiping Wang, Li Wang, Linxi Zhou, Lu Chen, Jiayi Shi, Jing Ge, Sha Tian, Zihan Yang, Yuqiong Zhou, Qihao Yu, Jiacheng Jin, Chen Ding, Yihuai Pan, Duohong Zou
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:International Journal of Oral Science
Online Access:https://doi.org/10.1038/s41368-025-00362-y
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