Case of the Diffuse Form of Xanthogranulomatous Pyelonephritis

Xanthogranulomatous pyelonephritis (XGP) is a rare entity and constitutes less than 1% of chronic pyelonephritis. A 71-year-old male was introduced to our department with general malaise and abnormal findings of computed tomography (CT). Abnormal findings of complete blood count and laboratory exami...

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Main Authors: Tateki Yoshino, Hiroyuki Moriyama
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2013/936035
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author Tateki Yoshino
Hiroyuki Moriyama
author_facet Tateki Yoshino
Hiroyuki Moriyama
author_sort Tateki Yoshino
collection DOAJ
description Xanthogranulomatous pyelonephritis (XGP) is a rare entity and constitutes less than 1% of chronic pyelonephritis. A 71-year-old male was introduced to our department with general malaise and abnormal findings of computed tomography (CT). Abnormal findings of complete blood count and laboratory examination included an elevated WBC count and C-reactive protein. Urinalysis showed combined hematuria and pyuria, and Escherichia coli was detected in urine culture. Abdominal CT revealed left hydronephrosis with staghorn renal calculi and thin cortex of the left kidney. Because of poor condition, the patient underwent construction of the left nephrostomy. After that, the remission of the inflammation was achieved. Several months after the construction, frequent obstructions of nephrostomy catheter because of turbid urine and intermittent fever elevation were observed. The patient and his family desired left nephrectomy despite his poor condition in general. Surgical dissection was very difficult due to fixed mass. Not long after that the patient died due to sepsis and cardiovascular failure. Microscopic findings of the left kidney revealed infiltration of lymphocytes and lipid-laden macrophages (xanthoma cells) corresponding to XGP.
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spelling doaj-art-79880bc1559e4cac9dd00a6b87d04bef2025-02-03T01:03:34ZengWileyCase Reports in Urology2090-696X2090-69782013-01-01201310.1155/2013/936035936035Case of the Diffuse Form of Xanthogranulomatous PyelonephritisTateki Yoshino0Hiroyuki Moriyama1Department of Urology, JA Onomichi General Hospital, 1-10-23 Hirahara, Hiroshima, Onomichi 722-0018, JapanDepartment of Urology, JA Onomichi General Hospital, 1-10-23 Hirahara, Hiroshima, Onomichi 722-0018, JapanXanthogranulomatous pyelonephritis (XGP) is a rare entity and constitutes less than 1% of chronic pyelonephritis. A 71-year-old male was introduced to our department with general malaise and abnormal findings of computed tomography (CT). Abnormal findings of complete blood count and laboratory examination included an elevated WBC count and C-reactive protein. Urinalysis showed combined hematuria and pyuria, and Escherichia coli was detected in urine culture. Abdominal CT revealed left hydronephrosis with staghorn renal calculi and thin cortex of the left kidney. Because of poor condition, the patient underwent construction of the left nephrostomy. After that, the remission of the inflammation was achieved. Several months after the construction, frequent obstructions of nephrostomy catheter because of turbid urine and intermittent fever elevation were observed. The patient and his family desired left nephrectomy despite his poor condition in general. Surgical dissection was very difficult due to fixed mass. Not long after that the patient died due to sepsis and cardiovascular failure. Microscopic findings of the left kidney revealed infiltration of lymphocytes and lipid-laden macrophages (xanthoma cells) corresponding to XGP.http://dx.doi.org/10.1155/2013/936035
spellingShingle Tateki Yoshino
Hiroyuki Moriyama
Case of the Diffuse Form of Xanthogranulomatous Pyelonephritis
Case Reports in Urology
title Case of the Diffuse Form of Xanthogranulomatous Pyelonephritis
title_full Case of the Diffuse Form of Xanthogranulomatous Pyelonephritis
title_fullStr Case of the Diffuse Form of Xanthogranulomatous Pyelonephritis
title_full_unstemmed Case of the Diffuse Form of Xanthogranulomatous Pyelonephritis
title_short Case of the Diffuse Form of Xanthogranulomatous Pyelonephritis
title_sort case of the diffuse form of xanthogranulomatous pyelonephritis
url http://dx.doi.org/10.1155/2013/936035
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