Treatment-Related Mechanisms of Tibetan Medicine <i>Terminalia chebula</i> (TC) Aqueous Extract Against Mouse Gastroenteritis Caused by Yak-Origin <i>Salmonella</i> Determined Using Intestinal Microbiome Analysis and Metabolomics

Treatment-Related Mechanisms of Tibetan Medicine <i>Terminalia chebula</i> (TC) Aqueous Extract Against Mouse Gastroenteritis Caused by Yak-Origin <i>Salmonella</i> Determined Using Intestinal Microbiome Analysis and Metabolomics

This study aimed to evaluate the therapeutic effect of <i>Terminalia chebula</i> (TC) on Tibetan yak-origin <i>Salmonella</i>-induced diarrhea and dysentery in mice. The levels of pro-inflammatory cytokines (IL-1β, IL-6, IL-8, and TNF-α), anti-inflammatory cytokines (IL-4 and...

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Bibliographic Details
Main Authors: Dengyu Li, Kaiqin Zhang, Xiaofeng Xue, Zhanchun Bai, La Yang, Jingjing Qi, Sizhu Suolang
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Animals
Subjects:
<i>Terminalia chebula</i> (TC)
gastroenteritis
gut microbiome
non-targeted metabolism
<i>Salmonella</i>
Online Access:https://www.mdpi.com/2076-2615/15/5/755
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