Corticostriatal Plastic Changes in Experimental L-DOPA-Induced Dyskinesia

Corticostriatal Plastic Changes in Experimental L-DOPA-Induced Dyskinesia

In Parkinson’s disease (PD), alteration of dopamine- (DA-) dependent striatal functions and pulsatile stimulation of DA receptors caused by the discontinuous administration of levodopa (L-DOPA) lead to a complex cascade of events affecting the postsynaptic striatal neurons that might account for the...

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Bibliographic Details
Main Authors: Veronica Ghiglieri, Vincenza Bagetta, Valentina Pendolino, Barbara Picconi, Paolo Calabresi
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/2012/358176
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