The Efficacy of Drug-Coated Balloon for Acute Coronary Syndrome
Background. Percutaneous coronary intervention using a drug-eluting stent (DES) is a common therapeutic option for acute coronary syndrome (ACS). However, stent-associated complications, such as bleeding associated with dual antiplatelet therapy, in-stent restenosis, stent thrombosis, and neoatheros...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2023/4594818 |
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| author | Hirokazu Naganawa Akira Ito Shinrou Saiki Daisuke Nishi Shinichi Takamatsu Yoshihisa Ito Takeshi Suzuki |
| author_facet | Hirokazu Naganawa Akira Ito Shinrou Saiki Daisuke Nishi Shinichi Takamatsu Yoshihisa Ito Takeshi Suzuki |
| author_sort | Hirokazu Naganawa |
| collection | DOAJ |
| description | Background. Percutaneous coronary intervention using a drug-eluting stent (DES) is a common therapeutic option for acute coronary syndrome (ACS). However, stent-associated complications, such as bleeding associated with dual antiplatelet therapy, in-stent restenosis, stent thrombosis, and neoatherosclerosis, remain. Drug-coated balloons (DCBs) are expected to reduce stent-associated complications. This study aimed to assess the efficacy of DCB therapy and compare it with that of DES therapy in patients with ACS. Materials and Methods. In this single-center, retrospective, observational study, we examined all patients with ACS treated with DCB or DES between July 2014 and November 2020. Patients with left main trunk lesions were excluded. The primary outcome was a composite of major adverse cardiovascular events (MACE: cardiac death, myocardial infarction, and target lesion revascularization) at one year. Results. Three hundred and seventy-two patients were treated with DES, and 83 patients were treated with DCB. MACE occurred in 10 (12.0%) patients in the DCB group and in 50 (13.4%) patients in the DES group (P=0.73). Conclusions. DCB is a valuable and effective therapy for patients with ACS. Moreover, DCB may become an alternative therapy for DES in patients with ACS. |
| format | Article |
| id | doaj-art-797017f4cc914c3ca9b41ebcc0c7cc80 |
| institution | OA Journals |
| issn | 2090-0597 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-797017f4cc914c3ca9b41ebcc0c7cc802025-08-20T02:07:17ZengWileyCardiology Research and Practice2090-05972023-01-01202310.1155/2023/4594818The Efficacy of Drug-Coated Balloon for Acute Coronary SyndromeHirokazu Naganawa0Akira Ito1Shinrou Saiki2Daisuke Nishi3Shinichi Takamatsu4Yoshihisa Ito5Takeshi Suzuki6Department of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyBackground. Percutaneous coronary intervention using a drug-eluting stent (DES) is a common therapeutic option for acute coronary syndrome (ACS). However, stent-associated complications, such as bleeding associated with dual antiplatelet therapy, in-stent restenosis, stent thrombosis, and neoatherosclerosis, remain. Drug-coated balloons (DCBs) are expected to reduce stent-associated complications. This study aimed to assess the efficacy of DCB therapy and compare it with that of DES therapy in patients with ACS. Materials and Methods. In this single-center, retrospective, observational study, we examined all patients with ACS treated with DCB or DES between July 2014 and November 2020. Patients with left main trunk lesions were excluded. The primary outcome was a composite of major adverse cardiovascular events (MACE: cardiac death, myocardial infarction, and target lesion revascularization) at one year. Results. Three hundred and seventy-two patients were treated with DES, and 83 patients were treated with DCB. MACE occurred in 10 (12.0%) patients in the DCB group and in 50 (13.4%) patients in the DES group (P=0.73). Conclusions. DCB is a valuable and effective therapy for patients with ACS. Moreover, DCB may become an alternative therapy for DES in patients with ACS.http://dx.doi.org/10.1155/2023/4594818 |
| spellingShingle | Hirokazu Naganawa Akira Ito Shinrou Saiki Daisuke Nishi Shinichi Takamatsu Yoshihisa Ito Takeshi Suzuki The Efficacy of Drug-Coated Balloon for Acute Coronary Syndrome Cardiology Research and Practice |
| title | The Efficacy of Drug-Coated Balloon for Acute Coronary Syndrome |
| title_full | The Efficacy of Drug-Coated Balloon for Acute Coronary Syndrome |
| title_fullStr | The Efficacy of Drug-Coated Balloon for Acute Coronary Syndrome |
| title_full_unstemmed | The Efficacy of Drug-Coated Balloon for Acute Coronary Syndrome |
| title_short | The Efficacy of Drug-Coated Balloon for Acute Coronary Syndrome |
| title_sort | efficacy of drug coated balloon for acute coronary syndrome |
| url | http://dx.doi.org/10.1155/2023/4594818 |
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