Health Consequences Among COVID-19 Convalescent Patients 30 Months Post-Infection in China
The health consequences among COVID-19 convalescent patients 30 months post-infection were described and the potential risk factors were determined. In August 2022 we recruited 217 COVID-19 convalescent patients who had been diagnosed with COVID-19 in February 2020. These convalescent patients were...
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| Format: | Article |
| Language: | English |
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Compuscript Ltd
2024-01-01
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| Series: | Zoonoses |
| Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2023-0014 |
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| author | Yu Yin Yi Guo Mingzhong Xiao Qinlin Chen Pinpin Long Xi Wang Jingzhi Wang Zuoyu Shao Yutong Qiu Yixuan Lu Yuchan Yang Xueqin Shi Wei Ni Shanshan Cheng Qi Wang Li Liu Tangchun Wu Xiaodong Li Hao Wang Yu Yuan |
| author_facet | Yu Yin Yi Guo Mingzhong Xiao Qinlin Chen Pinpin Long Xi Wang Jingzhi Wang Zuoyu Shao Yutong Qiu Yixuan Lu Yuchan Yang Xueqin Shi Wei Ni Shanshan Cheng Qi Wang Li Liu Tangchun Wu Xiaodong Li Hao Wang Yu Yuan |
| author_sort | Yu Yin |
| collection | DOAJ |
| description | The health consequences among COVID-19 convalescent patients 30 months post-infection were described and the potential risk factors were determined. In August 2022 we recruited 217 COVID-19 convalescent patients who had been diagnosed with COVID-19 in February 2020. These convalescent patients were residents of multiple districts in Wuhan, China. All convalescent patients completed a detailed questionnaire, laboratory testing, a 6-min walk test, a Borg dyspnea scale assessment, lung function testing, and had a chest CT. The potential risk factors for health consequences among COVID-19 convalescent patients 30 months post-infection were identified using a multivariate logistic regression model. The majority of convalescent patients were in good overall health and returned to work 30 months post-infection; however, 62.2% of the convalescent patients had long COVID symptoms. The most common symptoms were chest pain, fatigue, and dizziness or headaches. The convalescent patients with severe symptoms had a significantly higher proportion of depression disorder ( P = 0.044) and lower health-related quality of life ( P = 0.034) compared to the convalescent patients with mild symptoms. Compared to convalescent patients who were not vaccinated, convalescent patients who received three vaccines had significantly less fatigue, lower anxiety and depression scores, and had a better health-related quality of life (all P < 0.05). Older age was associated with a higher risk of long COVID (OR = 1.52, 95% CI = 1.16–2.02) and chest CT abnormalities (OR = 1.75, 95% CI = 1.33–2.36). Female gender was associated with a higher risk of anxiety (OR = 3.20, 95% CI = 1.24–9.16) and depression disorders (OR = 2.49, 95% CI = 1.11–5.92). Exercise was associated with a lower risk of anxiety (OR = 0.41, 95% CI = 0.18–0.93). Notably, vaccination protected convalescent patients from developing long COVID symptoms (OR = 0.18, 95% CI = 0.06–0.50), anxiety disorders (OR = 0.22, 95% CI = 0.07–0.71), and depression disorders (OR = 0.33, 95% CI = 0.12–0.92). The majority of COVID-19 convalescent patients were in good overall health 30 months post-infection and returned to work. More attention should be paid to convalescent patients who are older, female, physically inactive, and not vaccinated. |
| format | Article |
| id | doaj-art-796f8fa2d9864c10868858bdc17ec666 |
| institution | Kabale University |
| issn | 2737-7466 2737-7474 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Compuscript Ltd |
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| series | Zoonoses |
| spelling | doaj-art-796f8fa2d9864c10868858bdc17ec6662025-08-20T03:50:16ZengCompuscript LtdZoonoses2737-74662737-74742024-01-014199910.15212/ZOONOSES-2023-0014Health Consequences Among COVID-19 Convalescent Patients 30 Months Post-Infection in ChinaYu YinYi GuoMingzhong XiaoQinlin ChenPinpin LongXi WangJingzhi WangZuoyu ShaoYutong QiuYixuan LuYuchan YangXueqin ShiWei NiShanshan ChengQi WangLi LiuTangchun WuXiaodong LiHao WangYu YuanThe health consequences among COVID-19 convalescent patients 30 months post-infection were described and the potential risk factors were determined. In August 2022 we recruited 217 COVID-19 convalescent patients who had been diagnosed with COVID-19 in February 2020. These convalescent patients were residents of multiple districts in Wuhan, China. All convalescent patients completed a detailed questionnaire, laboratory testing, a 6-min walk test, a Borg dyspnea scale assessment, lung function testing, and had a chest CT. The potential risk factors for health consequences among COVID-19 convalescent patients 30 months post-infection were identified using a multivariate logistic regression model. The majority of convalescent patients were in good overall health and returned to work 30 months post-infection; however, 62.2% of the convalescent patients had long COVID symptoms. The most common symptoms were chest pain, fatigue, and dizziness or headaches. The convalescent patients with severe symptoms had a significantly higher proportion of depression disorder ( P = 0.044) and lower health-related quality of life ( P = 0.034) compared to the convalescent patients with mild symptoms. Compared to convalescent patients who were not vaccinated, convalescent patients who received three vaccines had significantly less fatigue, lower anxiety and depression scores, and had a better health-related quality of life (all P < 0.05). Older age was associated with a higher risk of long COVID (OR = 1.52, 95% CI = 1.16–2.02) and chest CT abnormalities (OR = 1.75, 95% CI = 1.33–2.36). Female gender was associated with a higher risk of anxiety (OR = 3.20, 95% CI = 1.24–9.16) and depression disorders (OR = 2.49, 95% CI = 1.11–5.92). Exercise was associated with a lower risk of anxiety (OR = 0.41, 95% CI = 0.18–0.93). Notably, vaccination protected convalescent patients from developing long COVID symptoms (OR = 0.18, 95% CI = 0.06–0.50), anxiety disorders (OR = 0.22, 95% CI = 0.07–0.71), and depression disorders (OR = 0.33, 95% CI = 0.12–0.92). The majority of COVID-19 convalescent patients were in good overall health 30 months post-infection and returned to work. More attention should be paid to convalescent patients who are older, female, physically inactive, and not vaccinated.https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2023-0014 |
| spellingShingle | Yu Yin Yi Guo Mingzhong Xiao Qinlin Chen Pinpin Long Xi Wang Jingzhi Wang Zuoyu Shao Yutong Qiu Yixuan Lu Yuchan Yang Xueqin Shi Wei Ni Shanshan Cheng Qi Wang Li Liu Tangchun Wu Xiaodong Li Hao Wang Yu Yuan Health Consequences Among COVID-19 Convalescent Patients 30 Months Post-Infection in China Zoonoses |
| title | Health Consequences Among COVID-19 Convalescent Patients 30 Months Post-Infection in China |
| title_full | Health Consequences Among COVID-19 Convalescent Patients 30 Months Post-Infection in China |
| title_fullStr | Health Consequences Among COVID-19 Convalescent Patients 30 Months Post-Infection in China |
| title_full_unstemmed | Health Consequences Among COVID-19 Convalescent Patients 30 Months Post-Infection in China |
| title_short | Health Consequences Among COVID-19 Convalescent Patients 30 Months Post-Infection in China |
| title_sort | health consequences among covid 19 convalescent patients 30 months post infection in china |
| url | https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2023-0014 |
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