Examining Demographic and Clinical Traits in Neurofibromatosis Type 1 Patients: Insights into Vitamin D Levels and Connections with Nevus Anemicus and Neurofibromas
Aim: This article aims to examine the demographic and clinical traits of neurofibromatosis type 1 (NF1) patients, particularly focusing on the potential links between vitamin D levels, BMI, and dermatological features. Methods: A retrospective review of medical records involving 128 patients diagnos...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Indian Journal of Dermatology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ijd.ijd_141_24 |
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| _version_ | 1841551922637570048 |
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| author | Vahid Ahmadi Nazli Karimi Arsoy S. Evans Ayşen Karaduman |
| author_facet | Vahid Ahmadi Nazli Karimi Arsoy S. Evans Ayşen Karaduman |
| author_sort | Vahid Ahmadi |
| collection | DOAJ |
| description | Aim:
This article aims to examine the demographic and clinical traits of neurofibromatosis type 1 (NF1) patients, particularly focusing on the potential links between vitamin D levels, BMI, and dermatological features.
Methods:
A retrospective review of medical records involving 128 patients diagnosed with neurofibromatosis type 1 (NF1) over a 3-year-period was conducted. The analysis emphasized investigating the demographic and clinical characteristics of the patients while evaluating key parameters.
Result:
Nevus anemicus was present in 32.8% of NF1 patients, and a significant association was found between nevus anemicus and low vitamin D levels (P = 0.001). We also observed a notable correlation between low vitamin D levels and an increased likelihood of neurofibromas (P < 0.001). Additionally, there appears to be an inverse relationship between serum vitamin D levels and the number of neurofibromas.
Conclusion:
Our study suggests a correlation between lower vitamin D levels and key dermatological characteristics in neurofibromatosis type 1 (NF1) individuals. Specifically, we observed associations with nevus anemicus prevalence and increased neurofibromas. This observation enriches NF1’s understanding, offering practical implications for patient management by emphasizing the importance of monitoring and addressing vitamin D levels. |
| format | Article |
| id | doaj-art-7966ddfe42c9494c973d60530c08b814 |
| institution | Kabale University |
| issn | 0019-5154 1998-3611 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dermatology |
| spelling | doaj-art-7966ddfe42c9494c973d60530c08b8142025-01-09T14:13:06ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112025-01-01701111710.4103/ijd.ijd_141_24Examining Demographic and Clinical Traits in Neurofibromatosis Type 1 Patients: Insights into Vitamin D Levels and Connections with Nevus Anemicus and NeurofibromasVahid AhmadiNazli KarimiArsoy S. EvansAyşen KaradumanAim: This article aims to examine the demographic and clinical traits of neurofibromatosis type 1 (NF1) patients, particularly focusing on the potential links between vitamin D levels, BMI, and dermatological features. Methods: A retrospective review of medical records involving 128 patients diagnosed with neurofibromatosis type 1 (NF1) over a 3-year-period was conducted. The analysis emphasized investigating the demographic and clinical characteristics of the patients while evaluating key parameters. Result: Nevus anemicus was present in 32.8% of NF1 patients, and a significant association was found between nevus anemicus and low vitamin D levels (P = 0.001). We also observed a notable correlation between low vitamin D levels and an increased likelihood of neurofibromas (P < 0.001). Additionally, there appears to be an inverse relationship between serum vitamin D levels and the number of neurofibromas. Conclusion: Our study suggests a correlation between lower vitamin D levels and key dermatological characteristics in neurofibromatosis type 1 (NF1) individuals. Specifically, we observed associations with nevus anemicus prevalence and increased neurofibromas. This observation enriches NF1’s understanding, offering practical implications for patient management by emphasizing the importance of monitoring and addressing vitamin D levels.https://journals.lww.com/10.4103/ijd.ijd_141_24demographic featuresneurofibromaneurofibromatosis type 1nevus anemicusvitamin dneurofibromatosis type 1clinicalnevus anemiscusneurofibromasvitamin d |
| spellingShingle | Vahid Ahmadi Nazli Karimi Arsoy S. Evans Ayşen Karaduman Examining Demographic and Clinical Traits in Neurofibromatosis Type 1 Patients: Insights into Vitamin D Levels and Connections with Nevus Anemicus and Neurofibromas Indian Journal of Dermatology demographic features neurofibroma neurofibromatosis type 1 nevus anemicus vitamin d neurofibromatosis type 1 clinical nevus anemiscus neurofibromas vitamin d |
| title | Examining Demographic and Clinical Traits in Neurofibromatosis Type 1 Patients: Insights into Vitamin D Levels and Connections with Nevus Anemicus and Neurofibromas |
| title_full | Examining Demographic and Clinical Traits in Neurofibromatosis Type 1 Patients: Insights into Vitamin D Levels and Connections with Nevus Anemicus and Neurofibromas |
| title_fullStr | Examining Demographic and Clinical Traits in Neurofibromatosis Type 1 Patients: Insights into Vitamin D Levels and Connections with Nevus Anemicus and Neurofibromas |
| title_full_unstemmed | Examining Demographic and Clinical Traits in Neurofibromatosis Type 1 Patients: Insights into Vitamin D Levels and Connections with Nevus Anemicus and Neurofibromas |
| title_short | Examining Demographic and Clinical Traits in Neurofibromatosis Type 1 Patients: Insights into Vitamin D Levels and Connections with Nevus Anemicus and Neurofibromas |
| title_sort | examining demographic and clinical traits in neurofibromatosis type 1 patients insights into vitamin d levels and connections with nevus anemicus and neurofibromas |
| topic | demographic features neurofibroma neurofibromatosis type 1 nevus anemicus vitamin d neurofibromatosis type 1 clinical nevus anemiscus neurofibromas vitamin d |
| url | https://journals.lww.com/10.4103/ijd.ijd_141_24 |
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