Prophylactic administration of lecithinized superoxide dismutase for a murine model of oxaliplatin-induced myelosuppression

BackgroundOxaliplatin, in combination with 5-fluorouracil and leucovorin, is a standard treatment for colorectal cancer and shows high efficacy. However, oxaliplatin induces side effects, such as chemotherapy-induced peripheral neuropathy and myelosuppression, which may lead to dose reduction, tempo...

Full description

Saved in:
Bibliographic Details
Main Authors: Mikako Shimoda, Akari Yamaguchi, Ayano Shikata, Yusuke Murakami, Masahiro Kawahara, Tohru Mizushima, Ken-ichiro Tanaka
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1607814/full
Tags: Add Tag
No Tags, Be the first to tag this record!