Comparison of circulating immune signatures across different consensus molecular subtypes (CMS) and between left- and right-sided lesions in stage II colorectal cancer using single-cell mass cytometry

Comparison of circulating immune signatures across different consensus molecular subtypes (CMS) and between left- and right-sided lesions in stage II colorectal cancer using single-cell mass cytometry

Abstract Background Patients with stage II colorectal cancer (CRC) show considerable variability in prognosis. Circulating immune cells play a vital role in systemic tumor surveillance. This study aimed to determine the clinical significance of the frequency and phenotype of circulating immune cell...

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Bibliographic Details
Main Authors: Pin Gao, Chuanyong Zhou, Hong Yang, Shunyu Deng, Beihai Jiang, Zaozao Wang, Jiabo Di, Xiangqian Su
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Translational Medicine
Subjects:
Stage II colorectal cancer
Immune signatures
Consensus molecular subtype
Tumor-sidedness
Single-cell mass cytometry
Online Access:https://doi.org/10.1186/s12967-025-06481-8
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