The GPR30 agonist G-1 promotes hair growth via Wnt/Hedgehog signaling in mice

The GPR30 agonist G-1 promotes hair growth via Wnt/Hedgehog signaling in mice

BackgroundGPR30 is a membrane-associated receptor involved in rapid, non-genomic estrogen signaling. Estrogen significantly influences hair growth and susceptibility to hair loss, with differences primarily driven by hormonal factors. While estrogen’s role in regulating hair follicle cycling is reco...

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Bibliographic Details
Main Authors: Mayu Yamano, Yuto Yamanaka, Shota Nishikawa, Yuki Masujima, Ryuji Ohue-Kitano, Ikuo Kimura
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
GPR30
estrogen
hair growth
G-1
Wnt/Hedgehog signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1570922/full
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