Identification and validation of prognostic genes associated with T-cell exhaustion and macrophage polarization in breast cancer

Identification and validation of prognostic genes associated with T-cell exhaustion and macrophage polarization in breast cancer

BackgroundThe most frequent malignant tumor in women is breast cancer (BRCA). It has been discovered that T-cell exhaustion and macrophages play significant roles in BRCA. It was necessary to explore prognostic genes associated with T-cell exhaustion and macrophage polarization in BRCA.MethodsThe fo...

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Bibliographic Details
Main Authors: Fengqiang Cui, Changjiao Yan, Jiang Wu, Yuqing Yang, Jixin Yang, Jialing Luo, Nanlin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Endocrinology
Subjects:
breast cancer
T-cell exhaustion
macrophage polarization
prognostic risk model
immune infiltration analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1556496/full
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