The Impact of Interleukin-6 and Hypoxia on the Expression of Brain Injury Marker Proteins in a Cellular Model of the Neurovascular Unit

The Impact of Interleukin-6 and Hypoxia on the Expression of Brain Injury Marker Proteins in a Cellular Model of the Neurovascular Unit

The high incidence of postoperative cognitive dysfunction in children undergoing cardiac surgery underscores the urgent need for effective neuroprotective strategies.Aim. To examine the effects of hypoxia and interleukin-6 (IL-6) on the expression of claudin-5, occludin-1, and interleukin-1 (IL-1) a...

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Bibliographic Details
Main Authors:	A. A. Ivkin, E. V. Grigoriev, E. D. Khilazheva
Format:	Article
Language:	English
Published:	Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2025-06-01
Series:	Общая реаниматология
Subjects:	neurovascular unit neurons astrocytes endothelial cells hypoxia interleukin-6 il-1 receptor claudin-5 occludin-1
Online Access:	https://www.reanimatology.com/rmt/article/view/2595
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