Striatal dopamine gene network moderates the effect of early adversity on the risk for adult psychiatric and cardiometabolic comorbidity

Striatal dopamine gene network moderates the effect of early adversity on the risk for adult psychiatric and cardiometabolic comorbidity

Abstract Cardiometabolic and psychiatric disorders often co-exist and share common early life risk factors, such as low birth weight. However, the biological pathways linking early adversity to adult cardiometabolic/psychiatric comorbidity remain unknown. Dopamine (DA) neurotransmission in the stria...

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Main Authors: Barbara Barth, Danusa Mar Arcego, Euclides José de Mendonça Filho, Randriely Merscher Sobreira de Lima, Carine Parent, Carla Dalmaz, André Krumel Portella, Irina Pokhvisneva, Michael J. Meaney, Patricia Pelufo Silveira
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-78465-5
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