Conservative Surgical Management of Stage I Bisphosphonate-Related Osteonecrosis of the Jaw
Purpose. To report the efficacy of conservative surgical treatment for stage I bisphosphonate-related osteonecrosis of the jaw (BRONJ). Materials and Methods. This study reports the clinical outcomes of 63 patients treated for BRONJ stage I (according to Ruggiero's staging system) at the Oral P...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | International Journal of Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2014/107690 |
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| author | Paolo Vescovi Elisabetta Merigo Marco Meleti Maddalena Manfredi Carlo Fornaini Samir Nammour Giovanni Mergoni Amin Sarraj Jose V. Bagan |
| author_facet | Paolo Vescovi Elisabetta Merigo Marco Meleti Maddalena Manfredi Carlo Fornaini Samir Nammour Giovanni Mergoni Amin Sarraj Jose V. Bagan |
| author_sort | Paolo Vescovi |
| collection | DOAJ |
| description | Purpose. To report the efficacy of conservative surgical treatment for stage I bisphosphonate-related osteonecrosis of the jaw (BRONJ). Materials and Methods. This study reports the clinical outcomes of 63 patients treated for BRONJ stage I (according to Ruggiero's staging system) at the Oral Pathology and Laser-Assisted Surgery Unit of the University of Parma between January 2004 and January 2011. Surgical interventions were performed, under local analgesia, in patients unresponsive for a period of six months to noninvasive treatments such as cycles of local or systemic antibacterial therapy combined or not to low level laser therapy, ozone therapy, or Hyperbaric Oxygen Therapy. All interventions were performed after the consultation of oncologist or physician. Results. In our experience, conservative surgical treatment is associated with the highest number of BRONJ healed sites in stage I disease. Complete healing was observed in 92.6% of sites surgically treated. Conclusions. This study confirms that treatment of patients affected by minimal bone exposition, (stage I of BRONJ), through conservative surgical strategies, possibly with laser, may result in a high control of the disease in the long term. |
| format | Article |
| id | doaj-art-7939880473944bb3a7389170c8ac5c52 |
| institution | Kabale University |
| issn | 1687-8728 1687-8736 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Dentistry |
| spelling | doaj-art-7939880473944bb3a7389170c8ac5c522025-02-03T06:11:30ZengWileyInternational Journal of Dentistry1687-87281687-87362014-01-01201410.1155/2014/107690107690Conservative Surgical Management of Stage I Bisphosphonate-Related Osteonecrosis of the JawPaolo Vescovi0Elisabetta Merigo1Marco Meleti2Maddalena Manfredi3Carlo Fornaini4Samir Nammour5Giovanni Mergoni6Amin Sarraj7Jose V. Bagan8Unit of Oral Pathology and Laser-Assisted Oral Surgery, Department of Biomedical, Biotechnological and Translational Sciences, University of Parma, 43100 Parma, ItalyUnit of Oral Pathology and Laser-Assisted Oral Surgery, Department of Biomedical, Biotechnological and Translational Sciences, University of Parma, 43100 Parma, ItalyUnit of Oral Pathology and Laser-Assisted Oral Surgery, Department of Biomedical, Biotechnological and Translational Sciences, University of Parma, 43100 Parma, ItalyUnit of Oral Pathology and Laser-Assisted Oral Surgery, Department of Biomedical, Biotechnological and Translational Sciences, University of Parma, 43100 Parma, ItalyUnit of Oral Pathology and Laser-Assisted Oral Surgery, Department of Biomedical, Biotechnological and Translational Sciences, University of Parma, 43100 Parma, ItalyUniversité de Liège, 4000 Liège, BelgiumUnit of Oral Pathology and Laser-Assisted Oral Surgery, Department of Biomedical, Biotechnological and Translational Sciences, University of Parma, 43100 Parma, ItalyUnit of Oral Pathology and Laser-Assisted Oral Surgery, Department of Biomedical, Biotechnological and Translational Sciences, University of Parma, 43100 Parma, ItalyUniversity of Valencia, 46010 Valencia, SpainPurpose. To report the efficacy of conservative surgical treatment for stage I bisphosphonate-related osteonecrosis of the jaw (BRONJ). Materials and Methods. This study reports the clinical outcomes of 63 patients treated for BRONJ stage I (according to Ruggiero's staging system) at the Oral Pathology and Laser-Assisted Surgery Unit of the University of Parma between January 2004 and January 2011. Surgical interventions were performed, under local analgesia, in patients unresponsive for a period of six months to noninvasive treatments such as cycles of local or systemic antibacterial therapy combined or not to low level laser therapy, ozone therapy, or Hyperbaric Oxygen Therapy. All interventions were performed after the consultation of oncologist or physician. Results. In our experience, conservative surgical treatment is associated with the highest number of BRONJ healed sites in stage I disease. Complete healing was observed in 92.6% of sites surgically treated. Conclusions. This study confirms that treatment of patients affected by minimal bone exposition, (stage I of BRONJ), through conservative surgical strategies, possibly with laser, may result in a high control of the disease in the long term.http://dx.doi.org/10.1155/2014/107690 |
| spellingShingle | Paolo Vescovi Elisabetta Merigo Marco Meleti Maddalena Manfredi Carlo Fornaini Samir Nammour Giovanni Mergoni Amin Sarraj Jose V. Bagan Conservative Surgical Management of Stage I Bisphosphonate-Related Osteonecrosis of the Jaw International Journal of Dentistry |
| title | Conservative Surgical Management of Stage I Bisphosphonate-Related Osteonecrosis of the Jaw |
| title_full | Conservative Surgical Management of Stage I Bisphosphonate-Related Osteonecrosis of the Jaw |
| title_fullStr | Conservative Surgical Management of Stage I Bisphosphonate-Related Osteonecrosis of the Jaw |
| title_full_unstemmed | Conservative Surgical Management of Stage I Bisphosphonate-Related Osteonecrosis of the Jaw |
| title_short | Conservative Surgical Management of Stage I Bisphosphonate-Related Osteonecrosis of the Jaw |
| title_sort | conservative surgical management of stage i bisphosphonate related osteonecrosis of the jaw |
| url | http://dx.doi.org/10.1155/2014/107690 |
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