Muscle stem cells in Duchenne muscular dystrophy exhibit molecular impairments and altered cell fate trajectories impacting regenerative capacity

Abstract Satellite cells are muscle-resident stem cells that maintain and repair muscle. Increasing evidence supports the contributing role of satellite cells in Duchenne muscular dystrophy (DMD), a lethal degenerative muscle disease caused by loss of dystrophin. However, whether or not satellite ce...

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Bibliographic Details
Main Authors: Jules A. Granet, Rebecca Robertson, Alessio A. Cusmano, Romina L. Filippelli, Tim O. Lorenz, Shulei Li, Moein Yaqubi, Jo Anne Stratton, Natasha C. Chang
Format: Article
Language:English
Published: Nature Publishing Group 2025-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07755-1
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