Correction of microecological imbalance in children who have suffered from multisystem inflammatory syndrome associated with SARS‐CoV‐2 in the post‐rehabilitation period
To conduct a study of the quality of life of children who have suffered from multisystem inflammatory syndrome (MIS‐C) associated with SARSCoV‐2 in the post‐rehabilitation period against the background of correction of microecological imbalance.The study involved 49 children aged 2 to 12 years who u...
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Kamerton
2024-07-01
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| Series: | Юг России: экология, развитие |
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| Online Access: | https://ecodag.elpub.ru/ugro/article/view/3145 |
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| author | T. I. Ryabichenko O. O. Obukhova M. I. Voevoda |
| author_facet | T. I. Ryabichenko O. O. Obukhova M. I. Voevoda |
| author_sort | T. I. Ryabichenko |
| collection | DOAJ |
| description | To conduct a study of the quality of life of children who have suffered from multisystem inflammatory syndrome (MIS‐C) associated with SARSCoV‐2 in the post‐rehabilitation period against the background of correction of microecological imbalance.The study involved 49 children aged 2 to 12 years who underwent MIS‐C associated with SARS‐CoV‐2 and received treatment in a hospital (DGKB No. 3 in Novosibirsk), and then underwent rehabilitation on an outpatient basis. The duration of rehabilitation was 7–8 weeks. All children were prescribed a course of additional rehabilitation for 30 days in order to correct microecological imbalance, which included: Biovestin, a dietary supplement in liquid form, containing bifidobacteria of the Bifidobacterium longum MC‐42 strain; the official drug, Kudesan, (active ingredient Coenzyme Q10); and the official drug, Succinic Acid. The assessment of physical, social, educational, emotional and psychological functioning, as well as quality of life as an integrating indicator before and after a comprehensive rehabilitation course using the parental form of the Reds OL Generic Core Scales questionnaire (Russian version) was carried out.After the rehabilitation course, children who underwent MIS‐C associated with SARS‐CoV‐2 showed signs of dysfunction of various organs and systems, which may be the result of an imbalance in the microbial ecosystem and requires mandatory correction. The introduction of a probiotic product and drugs affecting metabolic processes into the rehabilitation course led to a decrease in inflammatory reactions, as well as normalisation of metabolic processes and increased oxygenation, which improved the condition of the children and their quality of life.Federal Research Center for Fundamental and Translational Medicine (FRC FTM), Siberian Branch, Russian Academy of Sciences |
| format | Article |
| id | doaj-art-792b2a9e8cef484e8891461b3df51cba |
| institution | Kabale University |
| issn | 1992-1098 2413-0958 |
| language | Russian |
| publishDate | 2024-07-01 |
| publisher | Kamerton |
| record_format | Article |
| series | Юг России: экология, развитие |
| spelling | doaj-art-792b2a9e8cef484e8891461b3df51cba2025-08-20T03:56:32ZrusKamertonЮг России: экология, развитие1992-10982413-09582024-07-0119261610.18470/1992-1098-2024-2-11377Correction of microecological imbalance in children who have suffered from multisystem inflammatory syndrome associated with SARS‐CoV‐2 in the post‐rehabilitation periodT. I. Ryabichenko0O. O. Obukhova1M. I. Voevoda2Federal Research Center for Fundamental and Translational Medicine (FRC FTM), Siberian Branch, Russian Academy of SciencesFederal Research Center for Fundamental and Translational Medicine (FRC FTM), Siberian Branch, Russian Academy of SciencesFederal Research Center for Fundamental and Translational Medicine (FRC FTM), Siberian Branch, Russian Academy of SciencesTo conduct a study of the quality of life of children who have suffered from multisystem inflammatory syndrome (MIS‐C) associated with SARSCoV‐2 in the post‐rehabilitation period against the background of correction of microecological imbalance.The study involved 49 children aged 2 to 12 years who underwent MIS‐C associated with SARS‐CoV‐2 and received treatment in a hospital (DGKB No. 3 in Novosibirsk), and then underwent rehabilitation on an outpatient basis. The duration of rehabilitation was 7–8 weeks. All children were prescribed a course of additional rehabilitation for 30 days in order to correct microecological imbalance, which included: Biovestin, a dietary supplement in liquid form, containing bifidobacteria of the Bifidobacterium longum MC‐42 strain; the official drug, Kudesan, (active ingredient Coenzyme Q10); and the official drug, Succinic Acid. The assessment of physical, social, educational, emotional and psychological functioning, as well as quality of life as an integrating indicator before and after a comprehensive rehabilitation course using the parental form of the Reds OL Generic Core Scales questionnaire (Russian version) was carried out.After the rehabilitation course, children who underwent MIS‐C associated with SARS‐CoV‐2 showed signs of dysfunction of various organs and systems, which may be the result of an imbalance in the microbial ecosystem and requires mandatory correction. The introduction of a probiotic product and drugs affecting metabolic processes into the rehabilitation course led to a decrease in inflammatory reactions, as well as normalisation of metabolic processes and increased oxygenation, which improved the condition of the children and their quality of life.Federal Research Center for Fundamental and Translational Medicine (FRC FTM), Siberian Branch, Russian Academy of Scienceshttps://ecodag.elpub.ru/ugro/article/view/3145childrenmicroаecologymultisystem inflammatory syndromesars‐cov‐2reds ol generic core scales questionnairequality of life |
| spellingShingle | T. I. Ryabichenko O. O. Obukhova M. I. Voevoda Correction of microecological imbalance in children who have suffered from multisystem inflammatory syndrome associated with SARS‐CoV‐2 in the post‐rehabilitation period Юг России: экология, развитие children microаecology multisystem inflammatory syndrome sars‐cov‐2 reds ol generic core scales questionnaire quality of life |
| title | Correction of microecological imbalance in children who have suffered from multisystem inflammatory syndrome associated with SARS‐CoV‐2 in the post‐rehabilitation period |
| title_full | Correction of microecological imbalance in children who have suffered from multisystem inflammatory syndrome associated with SARS‐CoV‐2 in the post‐rehabilitation period |
| title_fullStr | Correction of microecological imbalance in children who have suffered from multisystem inflammatory syndrome associated with SARS‐CoV‐2 in the post‐rehabilitation period |
| title_full_unstemmed | Correction of microecological imbalance in children who have suffered from multisystem inflammatory syndrome associated with SARS‐CoV‐2 in the post‐rehabilitation period |
| title_short | Correction of microecological imbalance in children who have suffered from multisystem inflammatory syndrome associated with SARS‐CoV‐2 in the post‐rehabilitation period |
| title_sort | correction of microecological imbalance in children who have suffered from multisystem inflammatory syndrome associated with sars cov 2 in the post rehabilitation period |
| topic | children microаecology multisystem inflammatory syndrome sars‐cov‐2 reds ol generic core scales questionnaire quality of life |
| url | https://ecodag.elpub.ru/ugro/article/view/3145 |
| work_keys_str_mv | AT tiryabichenko correctionofmicroecologicalimbalanceinchildrenwhohavesufferedfrommultisysteminflammatorysyndromeassociatedwithsarscov2inthepostrehabilitationperiod AT ooobukhova correctionofmicroecologicalimbalanceinchildrenwhohavesufferedfrommultisysteminflammatorysyndromeassociatedwithsarscov2inthepostrehabilitationperiod AT mivoevoda correctionofmicroecologicalimbalanceinchildrenwhohavesufferedfrommultisysteminflammatorysyndromeassociatedwithsarscov2inthepostrehabilitationperiod |