Neural correlates of visual object recognition in rats
Summary: Invariant object recognition—the ability to recognize objects across size, rotation, or context—is fundamental for making sense of a dynamic visual world. Though traditionally studied in primates, emerging evidence suggests rodents recognize objects across a range of identity-preserving tra...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-04-01
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| Series: | Cell Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124725002323 |
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| author | Juliana Y. Rhee César Echavarría Edward Soucy Joel Greenwood Javier A. Masís David D. Cox |
| author_facet | Juliana Y. Rhee César Echavarría Edward Soucy Joel Greenwood Javier A. Masís David D. Cox |
| author_sort | Juliana Y. Rhee |
| collection | DOAJ |
| description | Summary: Invariant object recognition—the ability to recognize objects across size, rotation, or context—is fundamental for making sense of a dynamic visual world. Though traditionally studied in primates, emerging evidence suggests rodents recognize objects across a range of identity-preserving transformations. We demonstrate that rats robustly perform visual object recognition and explore a neural pathway that may underlie this capacity by developing a pipeline from high-throughput behavior training to cellular resolution imaging in awake, head-fixed animals. Leveraging our optical approach, we systematically profile neurons in primary and higher-order visual areas and their spatial organization. We find that rat visual cortex exhibits several features similar to those observed in the primate ventral stream but also marked deviations, suggesting species-specific differences in how brains solve visual object recognition. This work reinforces the sophisticated visual abilities of rats and offers the technical foundation to use them as a powerful model for mechanistic perception. |
| format | Article |
| id | doaj-art-79256311f99c4cdca7013d302741fd7c |
| institution | Kabale University |
| issn | 2211-1247 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Cell Reports |
| spelling | doaj-art-79256311f99c4cdca7013d302741fd7c2025-08-20T03:44:27ZengElsevierCell Reports2211-12472025-04-0144411546110.1016/j.celrep.2025.115461Neural correlates of visual object recognition in ratsJuliana Y. Rhee0César Echavarría1Edward Soucy2Joel Greenwood3Javier A. Masís4David D. Cox5The Rockefeller University, New York, NY 10065, USA; Center for Brain Science, Harvard University, Cambridge, MA 02138, USA; Corresponding authorCenter for Brain Science, Harvard University, Cambridge, MA 02138, USACenter for Brain Science, Harvard University, Cambridge, MA 02138, USACenter for Brain Science, Harvard University, Cambridge, MA 02138, USA; Kavli Center for Neurotechnology, Yale University, New Haven, CT 06510, USACenter for Brain Science, Harvard University, Cambridge, MA 02138, USA; Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USACenter for Brain Science, Harvard University, Cambridge, MA 02138, USA; IBM Research, Cambridge, MA 02142, USASummary: Invariant object recognition—the ability to recognize objects across size, rotation, or context—is fundamental for making sense of a dynamic visual world. Though traditionally studied in primates, emerging evidence suggests rodents recognize objects across a range of identity-preserving transformations. We demonstrate that rats robustly perform visual object recognition and explore a neural pathway that may underlie this capacity by developing a pipeline from high-throughput behavior training to cellular resolution imaging in awake, head-fixed animals. Leveraging our optical approach, we systematically profile neurons in primary and higher-order visual areas and their spatial organization. We find that rat visual cortex exhibits several features similar to those observed in the primate ventral stream but also marked deviations, suggesting species-specific differences in how brains solve visual object recognition. This work reinforces the sophisticated visual abilities of rats and offers the technical foundation to use them as a powerful model for mechanistic perception.http://www.sciencedirect.com/science/article/pii/S2211124725002323CP: Neuroscience |
| spellingShingle | Juliana Y. Rhee César Echavarría Edward Soucy Joel Greenwood Javier A. Masís David D. Cox Neural correlates of visual object recognition in rats Cell Reports CP: Neuroscience |
| title | Neural correlates of visual object recognition in rats |
| title_full | Neural correlates of visual object recognition in rats |
| title_fullStr | Neural correlates of visual object recognition in rats |
| title_full_unstemmed | Neural correlates of visual object recognition in rats |
| title_short | Neural correlates of visual object recognition in rats |
| title_sort | neural correlates of visual object recognition in rats |
| topic | CP: Neuroscience |
| url | http://www.sciencedirect.com/science/article/pii/S2211124725002323 |
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