How does the cut-off point for grip strength affect the prevalence of sarcopenia and associated factors? Findings from the ELSI-Brazil Study
Abstract: This study aimed to compare the prevalence of sarcopenia and associated factors with the definition of muscle weakness established using two different cut-off points for grip strength. We carried out a cross-sectional study with 7,065 participants (aged 50 or older) from the ELSI-Brazil St...
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Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
2025-06-01
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| Series: | Cadernos de Saúde Pública |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2025000501408&lng=en&tlng=en |
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| author | Sara Souza Lima Roberta de Oliveira Máximo Mariane Marques Luiz Patrícia Silva Tofani Letícia Coelho Silveira Thales Batista de Souza Thaís Barros Pereira da Silva Valdete Regina Guandalini Maria Fernanda Lima-Costa Cesar Messias de Oliveira Tiago da Silva Alexandre |
| author_facet | Sara Souza Lima Roberta de Oliveira Máximo Mariane Marques Luiz Patrícia Silva Tofani Letícia Coelho Silveira Thales Batista de Souza Thaís Barros Pereira da Silva Valdete Regina Guandalini Maria Fernanda Lima-Costa Cesar Messias de Oliveira Tiago da Silva Alexandre |
| author_sort | Sara Souza Lima |
| collection | DOAJ |
| description | Abstract: This study aimed to compare the prevalence of sarcopenia and associated factors with the definition of muscle weakness established using two different cut-off points for grip strength. We carried out a cross-sectional study with 7,065 participants (aged 50 or older) from the ELSI-Brazil Study. Sarcopenia was defined by the European Working Group on Sarcopenia in Older People (EWGSOP2) and two different cut-off points for grip strength to define weakness: < 27kg for men/< 16kg for women or < 36kg for men < 23kg for women. The prevalence of different sarcopenia status was estimated, and associations with sociodemographic, behavioral, and clinical factors were investigated using multinomial regression models. The mean age of participants was 61 years; 51.8% were women and 41.5% were at risk of malnutrition. By adopting the higher cut-off points (< 36kg/< 23kg) for the definition of weakness, the prevalence of probable sarcopenia and sarcopenia quadrupled (40.1% versus 10.6%; 5% versus 1.4%, respectively) and the prevalence of severe sarcopenia doubled (8.8 versus 3.9%). Nutritional status was associated with sarcopenia status, however the cut-off points < 36/< 23kg increased substantially the relative risk ratio between malnutrition and severe sarcopenia (RRR = 11.23 versus 6.45). In general, factors associated with sarcopenia status were similar irrespective of the cut-off point adopted. Higher cut-off points for the definition of weakness may be better for identifying sarcopenia, enabling early interventions to avoid adverse outcomes related to the disease. |
| format | Article |
| id | doaj-art-7924f8a307fc46dbacdf70cb534fb7d8 |
| institution | DOAJ |
| issn | 1678-4464 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz |
| record_format | Article |
| series | Cadernos de Saúde Pública |
| spelling | doaj-art-7924f8a307fc46dbacdf70cb534fb7d82025-08-20T03:10:58ZengEscola Nacional de Saúde Pública, Fundação Oswaldo CruzCadernos de Saúde Pública1678-44642025-06-0141510.1590/0102-311xen155624How does the cut-off point for grip strength affect the prevalence of sarcopenia and associated factors? Findings from the ELSI-Brazil StudySara Souza Limahttps://orcid.org/0000-0002-0215-4746Roberta de Oliveira Máximohttps://orcid.org/0000-0001-9757-9458Mariane Marques Luizhttps://orcid.org/0000-0001-5563-6354Patrícia Silva Tofanihttps://orcid.org/0000-0002-8065-6100Letícia Coelho Silveirahttps://orcid.org/0000-0002-5215-7937Thales Batista de Souzahttps://orcid.org/0000-0003-3534-1174Thaís Barros Pereira da Silvahttps://orcid.org/0000-0001-8554-8638Valdete Regina Guandalinihttps://orcid.org/0000-0003-2266-6113Maria Fernanda Lima-Costahttps://orcid.org/0000-0002-3474-2980Cesar Messias de Oliveirahttps://orcid.org/0000-0002-4099-4762Tiago da Silva Alexandrehttps://orcid.org/0000-0003-3791-9793Abstract: This study aimed to compare the prevalence of sarcopenia and associated factors with the definition of muscle weakness established using two different cut-off points for grip strength. We carried out a cross-sectional study with 7,065 participants (aged 50 or older) from the ELSI-Brazil Study. Sarcopenia was defined by the European Working Group on Sarcopenia in Older People (EWGSOP2) and two different cut-off points for grip strength to define weakness: < 27kg for men/< 16kg for women or < 36kg for men < 23kg for women. The prevalence of different sarcopenia status was estimated, and associations with sociodemographic, behavioral, and clinical factors were investigated using multinomial regression models. The mean age of participants was 61 years; 51.8% were women and 41.5% were at risk of malnutrition. By adopting the higher cut-off points (< 36kg/< 23kg) for the definition of weakness, the prevalence of probable sarcopenia and sarcopenia quadrupled (40.1% versus 10.6%; 5% versus 1.4%, respectively) and the prevalence of severe sarcopenia doubled (8.8 versus 3.9%). Nutritional status was associated with sarcopenia status, however the cut-off points < 36/< 23kg increased substantially the relative risk ratio between malnutrition and severe sarcopenia (RRR = 11.23 versus 6.45). In general, factors associated with sarcopenia status were similar irrespective of the cut-off point adopted. Higher cut-off points for the definition of weakness may be better for identifying sarcopenia, enabling early interventions to avoid adverse outcomes related to the disease.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2025000501408&lng=en&tlng=enSarcopeniaGrip StrengthPrevalence |
| spellingShingle | Sara Souza Lima Roberta de Oliveira Máximo Mariane Marques Luiz Patrícia Silva Tofani Letícia Coelho Silveira Thales Batista de Souza Thaís Barros Pereira da Silva Valdete Regina Guandalini Maria Fernanda Lima-Costa Cesar Messias de Oliveira Tiago da Silva Alexandre How does the cut-off point for grip strength affect the prevalence of sarcopenia and associated factors? Findings from the ELSI-Brazil Study Cadernos de Saúde Pública Sarcopenia Grip Strength Prevalence |
| title | How does the cut-off point for grip strength affect the prevalence of sarcopenia and associated factors? Findings from the ELSI-Brazil Study |
| title_full | How does the cut-off point for grip strength affect the prevalence of sarcopenia and associated factors? Findings from the ELSI-Brazil Study |
| title_fullStr | How does the cut-off point for grip strength affect the prevalence of sarcopenia and associated factors? Findings from the ELSI-Brazil Study |
| title_full_unstemmed | How does the cut-off point for grip strength affect the prevalence of sarcopenia and associated factors? Findings from the ELSI-Brazil Study |
| title_short | How does the cut-off point for grip strength affect the prevalence of sarcopenia and associated factors? Findings from the ELSI-Brazil Study |
| title_sort | how does the cut off point for grip strength affect the prevalence of sarcopenia and associated factors findings from the elsi brazil study |
| topic | Sarcopenia Grip Strength Prevalence |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2025000501408&lng=en&tlng=en |
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