Combined Kidney-Liver, Heart-Liver, and Kidney-Pancreas Transplantations from a Single Deceased Donor

Splitting the liver for two adults to increase the donor pool is still a debated issue, especially for combined organ transplantation. We described a case of liver-splitting procedure for two adults, which was successful even in the presence of combined organ transplantation. Three adult combined or...

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Main Authors: Matteo Ravaioli, Matteo Serenari, Matteo Cescon, Sofia Martin Suarez, Alessandro Cucchetti, Giorgio Ercolani, Massimo Del Gaudio, Fausto Catena, Cristina Morelli, Giorgio Arpesella, Antonio Daniele Pinna
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Transplantation
Online Access:http://dx.doi.org/10.1155/2012/849619
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author Matteo Ravaioli
Matteo Serenari
Matteo Cescon
Sofia Martin Suarez
Alessandro Cucchetti
Giorgio Ercolani
Massimo Del Gaudio
Fausto Catena
Cristina Morelli
Giorgio Arpesella
Antonio Daniele Pinna
author_facet Matteo Ravaioli
Matteo Serenari
Matteo Cescon
Sofia Martin Suarez
Alessandro Cucchetti
Giorgio Ercolani
Massimo Del Gaudio
Fausto Catena
Cristina Morelli
Giorgio Arpesella
Antonio Daniele Pinna
author_sort Matteo Ravaioli
collection DOAJ
description Splitting the liver for two adults to increase the donor pool is still a debated issue, especially for combined organ transplantation. We described a case of liver-splitting procedure for two adults, which was successful even in the presence of combined organ transplantation. Three adult combined organ transplantations from one deceased donor were performed, with, use of split liver grafts in two patients: a combined heart-right split liver, a left kidney-left split liver, and a right kidney-pancreas transplantation. Despite a not perfect match between the graft type and recipient, the prevention of small-for-size syndrome by ligature of the splenic artery, and/or hemiportocaval shunt in the patient receiving the left split liver, and the maximal reduction of ischemia time were the main factors contributing to the success of the procedure. This is the first report of combined heart and split liver in two adults which may suggest new strategies for organ transplantations.
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institution Kabale University
issn 2090-6943
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language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series Case Reports in Transplantation
spelling doaj-art-791fd6175397473f8fb9457066460b732025-02-03T05:45:25ZengWileyCase Reports in Transplantation2090-69432090-69512012-01-01201210.1155/2012/849619849619Combined Kidney-Liver, Heart-Liver, and Kidney-Pancreas Transplantations from a Single Deceased DonorMatteo Ravaioli0Matteo Serenari1Matteo Cescon2Sofia Martin Suarez3Alessandro Cucchetti4Giorgio Ercolani5Massimo Del Gaudio6Fausto Catena7Cristina Morelli8Giorgio Arpesella9Antonio Daniele Pinna10Department of Liver and Multi-organ Transplantation, Sant 'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalyDepartment of Liver and Multi-organ Transplantation, Sant 'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalyDepartment of Liver and Multi-organ Transplantation, Sant 'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalyHeart and Lung Transplantation Program, Department of Cardiac Surgery, Sant 'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalyDepartment of Liver and Multi-organ Transplantation, Sant 'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalyDepartment of Liver and Multi-organ Transplantation, Sant 'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalyDepartment of Liver and Multi-organ Transplantation, Sant 'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalyDepartment of Liver and Multi-organ Transplantation, Sant 'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalyDepartment of Liver and Multi-organ Transplantation, Sant 'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalyHeart and Lung Transplantation Program, Department of Cardiac Surgery, Sant 'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalyDepartment of Liver and Multi-organ Transplantation, Sant 'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalySplitting the liver for two adults to increase the donor pool is still a debated issue, especially for combined organ transplantation. We described a case of liver-splitting procedure for two adults, which was successful even in the presence of combined organ transplantation. Three adult combined organ transplantations from one deceased donor were performed, with, use of split liver grafts in two patients: a combined heart-right split liver, a left kidney-left split liver, and a right kidney-pancreas transplantation. Despite a not perfect match between the graft type and recipient, the prevention of small-for-size syndrome by ligature of the splenic artery, and/or hemiportocaval shunt in the patient receiving the left split liver, and the maximal reduction of ischemia time were the main factors contributing to the success of the procedure. This is the first report of combined heart and split liver in two adults which may suggest new strategies for organ transplantations.http://dx.doi.org/10.1155/2012/849619
spellingShingle Matteo Ravaioli
Matteo Serenari
Matteo Cescon
Sofia Martin Suarez
Alessandro Cucchetti
Giorgio Ercolani
Massimo Del Gaudio
Fausto Catena
Cristina Morelli
Giorgio Arpesella
Antonio Daniele Pinna
Combined Kidney-Liver, Heart-Liver, and Kidney-Pancreas Transplantations from a Single Deceased Donor
Case Reports in Transplantation
title Combined Kidney-Liver, Heart-Liver, and Kidney-Pancreas Transplantations from a Single Deceased Donor
title_full Combined Kidney-Liver, Heart-Liver, and Kidney-Pancreas Transplantations from a Single Deceased Donor
title_fullStr Combined Kidney-Liver, Heart-Liver, and Kidney-Pancreas Transplantations from a Single Deceased Donor
title_full_unstemmed Combined Kidney-Liver, Heart-Liver, and Kidney-Pancreas Transplantations from a Single Deceased Donor
title_short Combined Kidney-Liver, Heart-Liver, and Kidney-Pancreas Transplantations from a Single Deceased Donor
title_sort combined kidney liver heart liver and kidney pancreas transplantations from a single deceased donor
url http://dx.doi.org/10.1155/2012/849619
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