High-Mobility Group Box-1 Protein Serum Levels Do Not Reflect Monocytic Function in Patients with Sepsis-Induced Immunosuppression

High-Mobility Group Box-1 Protein Serum Levels Do Not Reflect Monocytic Function in Patients with Sepsis-Induced Immunosuppression

Background. High-mobility group box-1 (HMGB-1) protein is released during “late sepsis” by activated monocytes. We investigated whether systemic HMGB-1 levels are associated with indices of monocytic activation/function in patients with sepsis-induced immunosuppression. Methodology. 36 patients (31...

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Bibliographic Details
Main Authors:	Nadine Unterwalder, Christian Meisel, Konstantinos Savvatis, Ben Hammoud, Christina Fotopoulou, Hans-Dieter Volk, Petra Reinke, Joerg C. Schefold
Format:	Article
Language:	English
Published:	Wiley 2010-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2010/745724
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