Endothelial sensitivity to pro-fibrotic signals links systemic exposure to pulmonary fibrosis

Abstract Pulmonary fibrosis (PF) is a life-threatening condition characterised by excessive extracellular matrix deposition and tissue scarring. While much of PF research has focused on alveolar epithelial cells and fibroblasts, endothelial cells have emerged as active contributors to the disease in...

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Bibliographic Details
Main Authors: Lena Möbus, Laura Ylä-Outinen, Luca Mannino, Giorgia Migliaccio, Karoliina Kosunen, Nicoletta D’Alessandro, Angela Serra, Dario Greco
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07824-5
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