McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review
A rare combination of severe volume depletion and electrolyte imbalance caused by a rectal villous adenoma is often referred to as the McKittrick-Wheelock syndrome. Patients usually seek medical care because of chronic hypersecretory diarrhea and display renal failure, metabolic acidosis, hyponatrem...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2019/3104187 |
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| author | Mireille Caron Charles-Etienne Dubrûle François Letarte Valéry Lemelin Alexandre Lafleur |
| author_facet | Mireille Caron Charles-Etienne Dubrûle François Letarte Valéry Lemelin Alexandre Lafleur |
| author_sort | Mireille Caron |
| collection | DOAJ |
| description | A rare combination of severe volume depletion and electrolyte imbalance caused by a rectal villous adenoma is often referred to as the McKittrick-Wheelock syndrome. Patients usually seek medical care because of chronic hypersecretory diarrhea and display renal failure, metabolic acidosis, hyponatremia, and hypokalemia. We report the case of a 68-year-old woman who presented with this condition but showed unusual features such as severe hypokalemia and metabolic alkalosis, without diarrhea. She subsequently underwent transanal endoscopic microsurgery (TEMS), an innovative procedure in the management of large rectal adenomas. We also provide a narrative review of the literature on this rare entity. |
| format | Article |
| id | doaj-art-78fa56da625b473587006f2e069812c7 |
| institution | OA Journals |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-78fa56da625b473587006f2e069812c72025-08-20T02:07:30ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362019-01-01201910.1155/2019/31041873104187McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative ReviewMireille Caron0Charles-Etienne Dubrûle1François Letarte2Valéry Lemelin3Alexandre Lafleur4Faculty of Medicine, Laval University, Québec City, QC, CanadaDepartment of Internal Medicine, CHU de Québec, Québec City, QC, CanadaDepartment of Surgery, CHU de Québec, Québec City, QC, CanadaDepartment of Gastroenterology, CHU de Québec, Québec City, QC, CanadaDepartment of Internal Medicine, CHU de Québec, Québec City, QC, CanadaA rare combination of severe volume depletion and electrolyte imbalance caused by a rectal villous adenoma is often referred to as the McKittrick-Wheelock syndrome. Patients usually seek medical care because of chronic hypersecretory diarrhea and display renal failure, metabolic acidosis, hyponatremia, and hypokalemia. We report the case of a 68-year-old woman who presented with this condition but showed unusual features such as severe hypokalemia and metabolic alkalosis, without diarrhea. She subsequently underwent transanal endoscopic microsurgery (TEMS), an innovative procedure in the management of large rectal adenomas. We also provide a narrative review of the literature on this rare entity.http://dx.doi.org/10.1155/2019/3104187 |
| spellingShingle | Mireille Caron Charles-Etienne Dubrûle François Letarte Valéry Lemelin Alexandre Lafleur McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review Case Reports in Gastrointestinal Medicine |
| title | McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review |
| title_full | McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review |
| title_fullStr | McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review |
| title_full_unstemmed | McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review |
| title_short | McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review |
| title_sort | mckittrick wheelock syndrome presenting with acute kidney injury and metabolic alkalosis case report and narrative review |
| url | http://dx.doi.org/10.1155/2019/3104187 |
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