Transcriptomic features of immune inflammation and neural plasticity associated with early neurological improvement in acute ischemic stroke patients with large vessel occlusion

Transcriptomic features of immune inflammation and neural plasticity associated with early neurological improvement in acute ischemic stroke patients with large vessel occlusion

BackgroundAcute ischemic stroke (AIS) caused by large vessel occlusion (LVO) is a leading cause of disability and mortality worldwide. Although endovascular thrombectomy (EVT) has significantly improved outcomes, many patients do not achieve early neurological improvement (ENI) despite timely reperf...

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Bibliographic Details
Main Authors: Dong Zhang, Xinying Jing, Ruinan Ma, Zhizhang Li, Xiaoguang Zhang, Ying Ding, Yunhua Yue
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Neuroscience
Subjects:
acute ischemic stroke
large vessel occlusion
early neurological improvement
transcriptomics
immune-inflammatory response
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1581758/full
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