Endurance training and pyruvate dehydrogenase kinase 4 (PDK4) inhibition combination is superior to each one alone in attenuating hyperketonemia/ketoacidosis in diabetic rats

Endurance training and pyruvate dehydrogenase kinase 4 (PDK4) inhibition combination is superior to each one alone in attenuating hyperketonemia/ketoacidosis in diabetic rats

Objective(s): While ketone bodies are not the main heart fuel, exercise may increase their uptake. This study aimed to investigate the effect of 6-week endurance training and Pyruvate dehydrogenase kinase 4 )PDK4( inhibition on ketone bodies metabolism in the heart of diabetic rats with emphasis on...

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Bibliographic Details
Main Authors: Hamed Rezaeinasab, Abdolhamid Habibi, Ramin Rezaei, Aref Basereh, Salva Yurista, Kayvan Khoramipour
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-01-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
dietary supplements
endurance training
gene expression
ketone bodies
ketosis
pyruvate dehydrogenase - kinase 4
Online Access:https://ijbms.mums.ac.ir/article_25002_07162d0b958cff13974867c66b9b9d0b.pdf
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