Report concerning results of proficiency testing laboratory on assay of tobramycine and nystatin by microbiological method
The present study describes the results obtained by the Microbiological Control Laboratory from Institute for Control of Biological Products and Veterinary Medicines after participating in the proficiency testing scheme study on microbiological assay of nystatin and tobramycin. The proficiency testi...
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| Format: | Article |
| Language: | English |
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Asociaţia Naţională a Fabricanţilor de Produse de Uz Veterinar
2013-05-01
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| Series: | Medicamentul Veterinar |
| Online Access: | http://www.veterinarypharmacon.com/docs/1205-2013-14-1-ART-6.eng.pdf |
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| _version_ | 1850054072560779264 |
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| author | Simona Sturzu Daniela Tirsinoaga Ioana Tihulca Alina Karina Draghici |
| author_facet | Simona Sturzu Daniela Tirsinoaga Ioana Tihulca Alina Karina Draghici |
| author_sort | Simona Sturzu |
| collection | DOAJ |
| description | The present study describes the results obtained by the Microbiological Control Laboratory from Institute for Control of Biological Products and Veterinary Medicines after participating in the proficiency testing scheme study on microbiological assay of nystatin and tobramycin. The proficiency testing scheme was organized by European Directorate for the Quality of Medicines and Health Care. The microbiological method consisted of a cylinderplate agar diffusion assay using Bacillus subtilis ATCC 6633 for tobramycin and Saccharomyces cerevisiae for nystatin as the test microorganism. The means of results were 108.70 % of label claim for nystatin and 104.70%of label claim for tobramicin. The Z scores were 0.14 for tobramycin and 1.40 for nystatin, the assigned value used for booth samples was 105.4% for tobramycin and 101.7% for nystatin. The performance of Microbiological Control Laboratory was very good for both samples. |
| format | Article |
| id | doaj-art-78ef00de89eb4b018f8cfc83bc67beeb |
| institution | DOAJ |
| issn | 1843-9527 2069-2463 |
| language | English |
| publishDate | 2013-05-01 |
| publisher | Asociaţia Naţională a Fabricanţilor de Produse de Uz Veterinar |
| record_format | Article |
| series | Medicamentul Veterinar |
| spelling | doaj-art-78ef00de89eb4b018f8cfc83bc67beeb2025-08-20T02:52:21ZengAsociaţia Naţională a Fabricanţilor de Produse de Uz VeterinarMedicamentul Veterinar1843-95272069-24632013-05-01718183Report concerning results of proficiency testing laboratory on assay of tobramycine and nystatin by microbiological methodSimona SturzuDaniela TirsinoagaIoana TihulcaAlina Karina DraghiciThe present study describes the results obtained by the Microbiological Control Laboratory from Institute for Control of Biological Products and Veterinary Medicines after participating in the proficiency testing scheme study on microbiological assay of nystatin and tobramycin. The proficiency testing scheme was organized by European Directorate for the Quality of Medicines and Health Care. The microbiological method consisted of a cylinderplate agar diffusion assay using Bacillus subtilis ATCC 6633 for tobramycin and Saccharomyces cerevisiae for nystatin as the test microorganism. The means of results were 108.70 % of label claim for nystatin and 104.70%of label claim for tobramicin. The Z scores were 0.14 for tobramycin and 1.40 for nystatin, the assigned value used for booth samples was 105.4% for tobramycin and 101.7% for nystatin. The performance of Microbiological Control Laboratory was very good for both samples.http://www.veterinarypharmacon.com/docs/1205-2013-14-1-ART-6.eng.pdf |
| spellingShingle | Simona Sturzu Daniela Tirsinoaga Ioana Tihulca Alina Karina Draghici Report concerning results of proficiency testing laboratory on assay of tobramycine and nystatin by microbiological method Medicamentul Veterinar |
| title | Report concerning results of proficiency testing laboratory on assay of tobramycine and nystatin by microbiological method |
| title_full | Report concerning results of proficiency testing laboratory on assay of tobramycine and nystatin by microbiological method |
| title_fullStr | Report concerning results of proficiency testing laboratory on assay of tobramycine and nystatin by microbiological method |
| title_full_unstemmed | Report concerning results of proficiency testing laboratory on assay of tobramycine and nystatin by microbiological method |
| title_short | Report concerning results of proficiency testing laboratory on assay of tobramycine and nystatin by microbiological method |
| title_sort | report concerning results of proficiency testing laboratory on assay of tobramycine and nystatin by microbiological method |
| url | http://www.veterinarypharmacon.com/docs/1205-2013-14-1-ART-6.eng.pdf |
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