Clinical and microbiological patterns in critically ill patients with catheter-associated UTI: A report from Iran
Introduction: Catheter-associated urinary tract infections (CAUTIs) are among the most common nosocomial infections with different clinical and microbiological characteristics. We studied these characteristics in critically ill patients. Methodology: This research was a cross-sectional study cond...
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The Journal of Infection in Developing Countries
2023-01-01
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| author | Mohammadreza Salehi Dariush Robati SeyedAhmad SeyedAlinaghi Arash Seifi Amir Aliramezani Seyed Ali Dehghan Manshadi Pegah Afarinesh Khaki Fariba Zamani |
| author_facet | Mohammadreza Salehi Dariush Robati SeyedAhmad SeyedAlinaghi Arash Seifi Amir Aliramezani Seyed Ali Dehghan Manshadi Pegah Afarinesh Khaki Fariba Zamani |
| author_sort | Mohammadreza Salehi |
| collection | DOAJ |
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Introduction: Catheter-associated urinary tract infections (CAUTIs) are among the most common nosocomial infections with different clinical and microbiological characteristics. We studied these characteristics in critically ill patients.
Methodology: This research was a cross-sectional study conducted on intensive care unit (ICU) patients with CAUTI. Patients’ demographic and clinical information and laboratory data, including causative microorganisms and antibiotic susceptibility tests, were recorded and analyzed. Finally, the differences between the patients who survived and died were compared.
Results: After reviewing 353 ICU cases, 80 patients with CAUTI were finally included in the study. The mean age was 55.9 ± 19.1 years, 43.7% were male and 56.3% were female. The mean length of infection development since hospitalisation and hospital stay were 14.7 (3–90) and 27.8 (5–98) days, respectively. The most common symptom was fever (80%). The microbiological identification showed that the most isolated microorganisms were Multidrug-resistant (MDR) Enterobacteriaceae (75%), Pseudomonas aeruginosa (8.8%), Gram-positive uropathogens (8.8%) and Acinetobacter baumannii (5%). Fifteen patients (18.8%) died among whom infections with A. baumannii (75%) and P. aeruginosa (57.1%) were associated with more death (p = 0.005).
Conclusions: Although A. baumannii and P. aeruginosa can be the most important pathogens for death, MDR Enterobacteriaceae are still a serious concern as causes of CAUTIs.
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| format | Article |
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| language | English |
| publishDate | 2023-01-01 |
| publisher | The Journal of Infection in Developing Countries |
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| spelling | doaj-art-78ee57d06ac846c99ceb769e1d4523692025-08-20T02:14:16ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802023-01-01170110.3855/jidc.17084Clinical and microbiological patterns in critically ill patients with catheter-associated UTI: A report from IranMohammadreza Salehi0Dariush Robati1SeyedAhmad SeyedAlinaghi2Arash Seifi3Amir Aliramezani4Seyed Ali Dehghan Manshadi5Pegah Afarinesh Khaki6Fariba Zamani7Research center for antibiotic stewardship and antimicrobial resistance, Department of Infectious Diseases, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranResearch center for antibiotic stewardship and antimicrobial resistance, Department of Infectious Diseases, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranIranian Research Center for HIV/AIDS, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranResearch center for antibiotic stewardship and antimicrobial resistance, Department of Infectious Diseases, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, PolandIranian Research Center for HIV/AIDS, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranCentral laboratory, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranResearch center for antibiotic stewardship and antimicrobial resistance, Department of Infectious Diseases, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran Introduction: Catheter-associated urinary tract infections (CAUTIs) are among the most common nosocomial infections with different clinical and microbiological characteristics. We studied these characteristics in critically ill patients. Methodology: This research was a cross-sectional study conducted on intensive care unit (ICU) patients with CAUTI. Patients’ demographic and clinical information and laboratory data, including causative microorganisms and antibiotic susceptibility tests, were recorded and analyzed. Finally, the differences between the patients who survived and died were compared. Results: After reviewing 353 ICU cases, 80 patients with CAUTI were finally included in the study. The mean age was 55.9 ± 19.1 years, 43.7% were male and 56.3% were female. The mean length of infection development since hospitalisation and hospital stay were 14.7 (3–90) and 27.8 (5–98) days, respectively. The most common symptom was fever (80%). The microbiological identification showed that the most isolated microorganisms were Multidrug-resistant (MDR) Enterobacteriaceae (75%), Pseudomonas aeruginosa (8.8%), Gram-positive uropathogens (8.8%) and Acinetobacter baumannii (5%). Fifteen patients (18.8%) died among whom infections with A. baumannii (75%) and P. aeruginosa (57.1%) were associated with more death (p = 0.005). Conclusions: Although A. baumannii and P. aeruginosa can be the most important pathogens for death, MDR Enterobacteriaceae are still a serious concern as causes of CAUTIs. https://jidc.org/index.php/journal/article/view/17084Catheter-Associated UTIEnterobacteriaceaeGram-negative uropathogensdeath |
| spellingShingle | Mohammadreza Salehi Dariush Robati SeyedAhmad SeyedAlinaghi Arash Seifi Amir Aliramezani Seyed Ali Dehghan Manshadi Pegah Afarinesh Khaki Fariba Zamani Clinical and microbiological patterns in critically ill patients with catheter-associated UTI: A report from Iran Journal of Infection in Developing Countries Catheter-Associated UTI Enterobacteriaceae Gram-negative uropathogens death |
| title | Clinical and microbiological patterns in critically ill patients with catheter-associated UTI: A report from Iran |
| title_full | Clinical and microbiological patterns in critically ill patients with catheter-associated UTI: A report from Iran |
| title_fullStr | Clinical and microbiological patterns in critically ill patients with catheter-associated UTI: A report from Iran |
| title_full_unstemmed | Clinical and microbiological patterns in critically ill patients with catheter-associated UTI: A report from Iran |
| title_short | Clinical and microbiological patterns in critically ill patients with catheter-associated UTI: A report from Iran |
| title_sort | clinical and microbiological patterns in critically ill patients with catheter associated uti a report from iran |
| topic | Catheter-Associated UTI Enterobacteriaceae Gram-negative uropathogens death |
| url | https://jidc.org/index.php/journal/article/view/17084 |
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