Caution on the severe damage of Gelsemium elegans poisoning: a case report on family poisoning and systematic review
ObjectiveThis study reports a familial Gelsemium elegans poisoning case and systematically evaluates the efficacy of gastric lavage in G. elegans intoxication through a meta-analysis.MethodsWe systematically searched PubMed, Web of Science, CNKI, and Wanfang Data (2000–2024). Eligible randomized con...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Public Health |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1633727/full |
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| Summary: | ObjectiveThis study reports a familial Gelsemium elegans poisoning case and systematically evaluates the efficacy of gastric lavage in G. elegans intoxication through a meta-analysis.MethodsWe systematically searched PubMed, Web of Science, CNKI, and Wanfang Data (2000–2024). Eligible randomized controlled trials and case reports comparing gastric lavage versus non-lavage approaches were included. Data were extracted from published studies, and pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using Mantel–Haenszel random-effects models.ResultsThirteen studies involving 160 patients demonstrated an overall in-hospital mortality of 18.75%. Gastric lavage suggested potential survival benefit compared to controls (OR 0.39; 95% CI 0.15–0.99; p = 0.62).ConclusionG. elegans poisoning is life-threatening, with severe cases rapidly progressing to respiratory/circulatory failure requiring urgent support. Gastric lavage may offer survival advantage in hemodynamically stable patients when performed with airway protection. Prompt respiratory support should be prioritized in the therapeutic management. |
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| ISSN: | 2296-2565 |